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Recommendations for the design, optimization, and qualification of cell-based assays used for the detection of neutralizing antibody responses elicited to biological therapeutics.
Gupta S, Indelicato SR, Jethwa V, Kawabata T, Kelley M, Mire-Sluis AR, Richards SM, Rup B, Shores E, Swanson SJ, Wakshull E. Gupta S, et al. Among authors: wakshull e. J Immunol Methods. 2007 Apr 10;321(1-2):1-18. doi: 10.1016/j.jim.2006.12.004. Epub 2007 Jan 12. J Immunol Methods. 2007. PMID: 17307199 Review.
Regarding confirmatory immunogenicity assays.
Coleman D, Hendricks R, Delarosa R, Wakshull E. Coleman D, et al. Among authors: wakshull e. J Pharm Biomed Anal. 2013 Oct;84:173-6. doi: 10.1016/j.jpba.2013.06.001. Epub 2013 Jun 19. J Pharm Biomed Anal. 2013. PMID: 23838084 No abstract available.
Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans.
Baruch A, Wong C, Chinn LW, Vaze A, Sonoda J, Gelzleichter T, Chen S, Lewin-Koh N, Morrow L, Dheerendra S, Boismenu R, Gutierrez J, Wakshull E, Wilson ME, Arora PS. Baruch A, et al. Among authors: wakshull e. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28992-29000. doi: 10.1073/pnas.2012073117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139537 Free PMC article. Clinical Trial.
28 results