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MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis.
Candiello E, Reato G, Verginelli F, Gambardella G, D Ambrosio A, Calandra N, Orzan F, Iuliano A, Albano R, Sassi F, Luraghi P, Comoglio PM, Bertotti A, Trusolino L, Boccaccio C. Candiello E, et al. Mol Oncol. 2023 Jul;17(7):1280-1301. doi: 10.1002/1878-0261.13408. Epub 2023 Mar 19. Mol Oncol. 2023. PMID: 36862005 Free PMC article.
Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition.
Verginelli F, Pisacane A, Gambardella G, D'Ambrosio A, Candiello E, Ferrio M, Panero M, Casorzo L, Benvenuti S, Cascardi E, Senetta R, Geuna E, Ballabio A, Montemurro F, Sapino A, Comoglio PM, Boccaccio C. Verginelli F, et al. Among authors: candiello e. Nat Commun. 2021 May 3;12(1):2498. doi: 10.1038/s41467-021-22643-w. Nat Commun. 2021. PMID: 33941777 Free PMC article.