Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
6 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.
J Med Chem. 2005 Sep 8;48(18):5639-43. doi: 10.1021/jm050392q.
J Med Chem. 2005.
PMID: 16134929
Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11.
Saulnier MG, Balasubramanian BN, Long BH, Frennesson DB, Ruediger E, Zimmermann K, Eummer JT, St Laurent DR, Stoffan KM, Naidu BN, Mahler M, Beaulieu F, Bachand C, Lee FY, Fairchild CR, Stadnick LK, Rose WC, Solomon C, Wong H, Martel A, Wright JJ, Kramer R, Langley DR, Vyas DM.
Saulnier MG, et al. Among authors: eummer jt.
J Med Chem. 2005 Apr 7;48(7):2258-61. doi: 10.1021/jm049090z.
J Med Chem. 2005.
PMID: 15801816
Item in Clipboard
Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model.
Balasubramanian BN, St Laurent DR, Saulnier MG, Long BH, Bachand C, Beaulieu F, Clarke W, Deshpande M, Eummer J, Fairchild CR, Frennesson DB, Kramer R, Lee FY, Mahler M, Martel A, Naidu BN, Rose WC, Russell J, Ruediger E, Solomon C, Stoffan KM, Wong H, Wright JJ, Zimmermann K, Vyas DM.
Balasubramanian BN, et al. Among authors: eummer j.
J Med Chem. 2004 Mar 25;47(7):1609-12. doi: 10.1021/jm034197s.
J Med Chem. 2004.
PMID: 15027851
Item in Clipboard
Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors.
Eummer JT, Gibbs BS, Zahn TJ, Sebolt-Leopold JS, Gibbs RA.
Eummer JT, et al.
Bioorg Med Chem. 1999 Feb;7(2):241-50. doi: 10.1016/s0968-0896(98)00202-8.
Bioorg Med Chem. 1999.
PMID: 10218815
Item in Clipboard
Stereospecific synthesis and biological evaluation of farnesyl diphosphate isomers.
Shao Y, Eummer JT, Gibbs RA.
Shao Y, et al. Among authors: eummer jt.
Org Lett. 1999 Aug 26;1(4):627-30. doi: 10.1021/ol990714i.
Org Lett. 1999.
PMID: 10823190
Item in Clipboard
Novel modifications to the farnesyl moiety of the a-factor lipopeptide pheromone from Saccharomyces cerevisiae: a role for isoprene modifications in ligand presentation.
Dawe AL, Becker JM, Jiang Y, Naider F, Eummer JT, Mu YQ, Gibbs RA.
Dawe AL, et al. Among authors: eummer jt.
Biochemistry. 1997 Oct 7;36(40):12036-44. doi: 10.1021/bi9709755.
Biochemistry. 1997.
PMID: 9315841
Item in Clipboard
Cite
Cite