Fadel F - Search Results

1

Structural and functional insights into the periplasmic detector domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa.

Ali-Ahmad A, Fadel F, Sebban-Kreuzer C, Ba M, Pélissier GD, Bornet O, Guerlesquin F, Bourne Y, Bordi C, Vincent F. Ali-Ahmad A, et al. Among authors: fadel f. Sci Rep. 2017 Sep 12;7(1):11262. doi: 10.1038/s41598-017-11361-3. Sci Rep. 2017. PMID: 28900144 Free PMC article.

2

The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa.

Chambonnier G, Roux L, Redelberger D, Fadel F, Filloux A, Sivaneson M, de Bentzmann S, Bordi C. Chambonnier G, et al. Among authors: fadel f. PLoS Genet. 2016 May 13;12(5):e1006032. doi: 10.1371/journal.pgen.1006032. eCollection 2016 May. PLoS Genet. 2016. PMID: 27176226 Free PMC article.

3

NMR assignments of the GacS histidine-kinase periplasmic detection domain from Pseudomonas aeruginosa PAO1.

Ali-Ahmad A, Bornet O, Fadel F, Bourne Y, Vincent F, Bordi C, Guerlesquin F, Sebban-Kreuzer C. Ali-Ahmad A, et al. Among authors: fadel f. Biomol NMR Assign. 2017 Apr;11(1):25-28. doi: 10.1007/s12104-016-9714-7. Epub 2016 Oct 6. Biomol NMR Assign. 2017. PMID: 27714507

4

Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase.

Debarnot C, Monneau YR, Roig-Zamboni V, Delauzun V, Le Narvor C, Richard E, Hénault J, Goulet A, Fadel F, Vivès RR, Priem B, Bonnaffé D, Lortat-Jacob H, Bourne Y. Debarnot C, et al. Among authors: fadel f. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6760-6765. doi: 10.1073/pnas.1818333116. Epub 2019 Mar 14. Proc Natl Acad Sci U S A. 2019. PMID: 30872481 Free PMC article.

5

Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS.

Fadel F, Bassim V, Francis VI, Porter SL, Botzanowski T, Legrand P, Perez MM, Bourne Y, Cianférani S, Vincent F. Fadel F, et al. Structure. 2022 Sep 1;30(9):1285-1297.e5. doi: 10.1016/j.str.2022.06.002. Epub 2022 Jun 28. Structure. 2022. PMID: 35767996 Free article.

6

Structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs.

Brüderlin M, Böhm R, Fadel F, Hiller S, Schirmer T, Dubey BN. Brüderlin M, et al. Among authors: fadel f. Nat Commun. 2023 Mar 2;14(1):1002. doi: 10.1038/s41467-023-36597-8. Nat Commun. 2023. PMID: 36864019 Free PMC article.

7

New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.

Fadel F, Zhao Y, Cachau R, Cousido-Siah A, Ruiz FX, Harlos K, Howard E, Mitschler A, Podjarny A. Fadel F, et al. Acta Crystallogr D Biol Crystallogr. 2015 Jul;71(Pt 7):1455-70. doi: 10.1107/S139900471500783X. Epub 2015 Jun 30. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26143917

8

High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution.

Howard EI, Guillot B, Blakeley MP, Haertlein M, Moulin M, Mitschler A, Cousido-Siah A, Fadel F, Valsecchi WM, Tomizaki T, Petrova T, Claudot J, Podjarny A. Howard EI, et al. Among authors: fadel f. IUCrJ. 2016 Jan 16;3(Pt 2):115-26. doi: 10.1107/S2052252515024161. eCollection 2016 Mar 1. IUCrJ. 2016. PMID: 27006775 Free PMC article.

9

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

Mazur M, Olczak J, Olejniczak S, Koralewski R, Czestkowski W, Jedrzejczak A, Golab J, Dzwonek K, Dymek B, Sklepkiewicz PL, Zagozdzon A, Noonan T, Mahboubi K, Conway B, Sheeler R, Beckett P, Hungerford WM, Podjarny A, Mitschler A, Cousido-Siah A, Fadel F, Golebiowski A. Mazur M, et al. Among authors: fadel f. J Med Chem. 2018 Feb 8;61(3):695-710. doi: 10.1021/acs.jmedchem.7b01051. Epub 2018 Jan 11. J Med Chem. 2018. PMID: 29283260

10

X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain.

Fadel F, Zhao Y, Cousido-Siah A, Ruiz FX, Mitschler A, Podjarny A. Fadel F, et al. PLoS One. 2016 Apr 25;11(4):e0154190. doi: 10.1371/journal.pone.0154190. eCollection 2016. PLoS One. 2016. PMID: 27111557 Free PMC article.

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