Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine.
Osborne CS, Leitner I, Favre B, Ryder NS.
Osborne CS, et al. Among authors: favre b.
Antimicrob Agents Chemother. 2005 Jul;49(7):2840-4. doi: 10.1128/AAC.49.7.2840-2844.2005.
Antimicrob Agents Chemother. 2005.
PMID: 15980358
Free PMC article.
Microsomal SE activity from these resistant isolates was insensitive to terbinafine, suggesting a target-based mechanism of resistance (B. Favre, M. Ghannoum, and N. S. Ryder, Med. Mycol. 42:525-529, 2004). ...
Microsomal SE activity from these resistant isolates was insensitive to terbinafine, suggesting a target-based mechanism of resistance (B …