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Page 1
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress.
De Lorenzo F, Lüningschrör P, Nam J, Beckett L, Pilotto F, Galli E, Lindholm P, Rüdt von Collenberg C, Mungwa ST, Jablonka S, Kauder J, Thau-Habermann N, Petri S, Lindholm D, Saxena S, Sendtner M, Saarma M, Voutilainen MH. De Lorenzo F, et al. Among authors: pilotto f. Brain. 2023 Sep 1;146(9):3783-3799. doi: 10.1093/brain/awad087. Brain. 2023. PMID: 36928391 Free PMC article.
Early molecular layer interneuron hyperactivity triggers Purkinje neuron degeneration in SCA1.
Pilotto F, Douthwaite C, Diab R, Ye X, Al Qassab Z, Tietje C, Mounassir M, Odriozola A, Thapa A, Buijsen RAM, Lagache S, Uldry AC, Heller M, Müller S, van Roon-Mom WMC, Zuber B, Liebscher S, Saxena S. Pilotto F, et al. Neuron. 2023 Aug 16;111(16):2523-2543.e10. doi: 10.1016/j.neuron.2023.05.016. Epub 2023 Jun 14. Neuron. 2023. PMID: 37321222 Free PMC article.
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder.
Gurgone A, Pizzo R, Raspanti A, Chiantia G, Devi S, Comai D, Morello N, Pilotto F, Gnavi S, Lupori L, Mazziotti R, Sagona G, Putignano E, Nocentini A, Supuran CT, Marcantoni A, Pizzorusso T, Giustetto M. Gurgone A, et al. Among authors: pilotto f. Neuropsychopharmacology. 2023 May;48(6):877-886. doi: 10.1038/s41386-022-01412-3. Epub 2022 Aug 9. Neuropsychopharmacology. 2023. PMID: 35945276 Free PMC article.
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Pilotto F, Schmitz A, Maharjan N, Diab R, Odriozola A, Tripathi P, Yamoah A, Scheidegger O, Oestmann A, Dennys CN, Sinha Ray S, Rodrigo R, Kolb S, Aronica E, Di Santo S, Widmer HR, Charlet-Berguerand N, Selvaraj BT, Chandran S, Meyer K, Zuber B, Goswami A, Weis J, Saxena S. Pilotto F, et al. Acta Neuropathol. 2022 Nov;144(5):939-966. doi: 10.1007/s00401-022-02494-5. Epub 2022 Sep 19. Acta Neuropathol. 2022. PMID: 36121477 Free PMC article.
Slow Waves Promote Sleep-Dependent Plasticity and Functional Recovery after Stroke.
Facchin L, Schöne C, Mensen A, Bandarabadi M, Pilotto F, Saxena S, Libourel PA, Bassetti CLA, Adamantidis AR. Facchin L, et al. Among authors: pilotto f. J Neurosci. 2020 Nov 4;40(45):8637-8651. doi: 10.1523/JNEUROSCI.0373-20.2020. Epub 2020 Oct 21. J Neurosci. 2020. PMID: 33087472 Free PMC article.
Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs.
Nguyen L, Laboissonniere LA, Guo S, Pilotto F, Scheidegger O, Oestmann A, Hammond JW, Li H, Hyysalo A, Peltola R, Pattamatta A, Zu T, Voutilainen MH, Gelbard HA, Saxena S, Ranum LPW. Nguyen L, et al. Among authors: pilotto f. Neuron. 2020 Nov 25;108(4):784-796.e3. doi: 10.1016/j.neuron.2020.09.009. Epub 2020 Oct 5. Neuron. 2020. PMID: 33022226 Free PMC article.
Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.
Morello N, Schina R, Pilotto F, Phillips M, Melani R, Plicato O, Pizzorusso T, Pozzo-Miller L, Giustetto M. Morello N, et al. Among authors: pilotto f. eNeuro. 2018 Sep 24;5(5):ENEURO.0086-18.2018. doi: 10.1523/ENEURO.0086-18.2018. eCollection 2018 Sep-Oct. eNeuro. 2018. PMID: 30255129 Free PMC article.