Fenton AW - Search Results

1

Benchmarking predictions of allostery in liver pyruvate kinase in CAGI4.

Xu Q, Tang Q, Katsonis P, Lichtarge O, Jones D, Bovo S, Babbi G, Martelli PL, Casadio R, Lee GR, Seok C, Fenton AW, Dunbrack RL Jr. Xu Q, et al. Among authors: fenton aw. Hum Mutat. 2017 Sep;38(9):1123-1131. doi: 10.1002/humu.23222. Epub 2017 May 2. Hum Mutat. 2017. PMID: 28370845 Free PMC article.

2

Mining for allosteric information: natural mutations and positional sequence conservation in pyruvate kinase.

Pendergrass DC, Williams R, Blair JB, Fenton AW. Pendergrass DC, et al. Among authors: fenton aw. IUBMB Life. 2006 Jan;58(1):31-8. doi: 10.1080/15216540500531705. IUBMB Life. 2006. PMID: 16540430 Free article.

3

An activating interaction between the unphosphorylated n-terminus of human liver pyruvate kinase and the main body of the protein is interrupted by phosphorylation.

Fenton AW, Tang Q. Fenton AW, et al. Biochemistry. 2009 May 12;48(18):3816-8. doi: 10.1021/bi900421f. Biochemistry. 2009. PMID: 19320443 Free PMC article.

4

The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine.

Fenton AW, Hutchinson M. Fenton AW, et al. Arch Biochem Biophys. 2009 Apr 1;484(1):16-23. doi: 10.1016/j.abb.2009.01.011. Epub 2009 Jan 20. Arch Biochem Biophys. 2009. PMID: 19467627 Free PMC article.

5

The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery.

Fenton AW, Johnson TA, Holyoak T. Fenton AW, et al. Protein Sci. 2010 Sep;19(9):1796-800. doi: 10.1002/pro.450. Protein Sci. 2010. PMID: 20629175 Free PMC article.

6

Effector analogues detect varied allosteric roles for conserved protein-effector interactions in pyruvate kinase isozymes.

Alontaga AY, Fenton AW. Alontaga AY, et al. Among authors: fenton aw. Biochemistry. 2011 Mar 22;50(11):1934-9. doi: 10.1021/bi200052e. Epub 2011 Feb 14. Biochemistry. 2011. PMID: 21261284 Free PMC article.

7

The impact of ions on allosteric functions in human liver pyruvate kinase.

Fenton AW, Alontaga AY. Fenton AW, et al. Methods Enzymol. 2009;466:83-107. doi: 10.1016/S0076-6879(09)66005-5. Epub 2009 Nov 13. Methods Enzymol. 2009. PMID: 21609859 Free PMC article.

8

Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus.

Prasannan CB, Tang Q, Fenton AW. Prasannan CB, et al. Among authors: fenton aw. Methods Mol Biol. 2012;796:335-49. doi: 10.1007/978-1-61779-334-9_18. Methods Mol Biol. 2012. PMID: 22052499 Free PMC article.

9

Identification of allosteric-activating drug leads for human liver pyruvate kinase.

Fenton AW. Fenton AW. Methods Mol Biol. 2012;796:369-82. doi: 10.1007/978-1-61779-334-9_20. Methods Mol Biol. 2012. PMID: 22052501 Free PMC article.

10

Distinguishing the chemical moiety of phosphoenolpyruvate that contributes to allostery in muscle pyruvate kinase.

Urness JM, Clapp KM, Timmons JC, Bai X, Chandrasoma N, Buszek KR, Fenton AW. Urness JM, et al. Among authors: fenton aw. Biochemistry. 2013 Jan 8;52(1):1-3. doi: 10.1021/bi301628k. Epub 2012 Dec 24. Biochemistry. 2013. PMID: 23256782 Free PMC article.

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