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Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.
Smith SJ, Cieslinski LB, Newton R, Donnelly LE, Fenwick PS, Nicholson AG, Barnes PJ, Barnette MS, Giembycz MA. Smith SJ, et al. Among authors: fenwick ps. Mol Pharmacol. 2004 Dec;66(6):1679-89. doi: 10.1124/mol.104.002246. Epub 2004 Sep 15. Mol Pharmacol. 2004. PMID: 15371556
Regulation of IL-17 in chronic inflammation in the human lung.
Pridgeon C, Bugeon L, Donnelly L, Straschil U, Tudhope SJ, Fenwick P, Lamb JR, Barnes PJ, Dallman MJ. Pridgeon C, et al. Clin Sci (Lond). 2011 Jun;120(12):515-24. doi: 10.1042/CS20100417. Clin Sci (Lond). 2011. PMID: 21208193
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