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Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.
Barallobre-Barreiro J, Didangelos A, Schoendube FA, Drozdov I, Yin X, Fernández-Caggiano M, Willeit P, Puntmann VO, Aldama-López G, Shah AM, Doménech N, Mayr M. Barallobre-Barreiro J, et al. Among authors: fernandez caggiano m. Circulation. 2012 Feb 14;125(6):789-802. doi: 10.1161/CIRCULATIONAHA.111.056952. Epub 2012 Jan 18. Circulation. 2012. PMID: 22261194 Free article.
Analysis of Mitochondrial Proteins in the Surviving Myocardium after Ischemia Identifies Mitochondrial Pyruvate Carrier Expression as Possible Mediator of Tissue Viability.
Fernández-Caggiano M, Prysyazhna O, Barallobre-Barreiro J, CalviñoSantos R, Aldama López G, Generosa Crespo-Leiro M, Eaton P, Doménech N. Fernández-Caggiano M, et al. Mol Cell Proteomics. 2016 Jan;15(1):246-55. doi: 10.1074/mcp.M115.051862. Epub 2015 Nov 18. Mol Cell Proteomics. 2016. PMID: 26582072 Free PMC article.
Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy.
Fernandez-Caggiano M, Kamynina A, Francois AA, Prysyazhna O, Eykyn TR, Krasemann S, Crespo-Leiro MG, Vieites MG, Bianchi K, Morales V, Domenech N, Eaton P. Fernandez-Caggiano M, et al. Nat Metab. 2020 Nov;2(11):1223-1231. doi: 10.1038/s42255-020-00276-5. Epub 2020 Oct 26. Nat Metab. 2020. PMID: 33106688 Free PMC article.
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.
De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS. De Nicola GF, et al. Among authors: fernandez caggiano m. JCI Insight. 2018 Aug 23;3(16):e121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135318 Free PMC article.
Reduced mitochondrial pyruvate carrier expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin.
Lopez-Vazquez P, Fernandez-Caggiano M, Barge-Caballero E, Barge-Caballero G, Couto-Mallon D, Grille-Cancela Z, Blanco-Canosa P, Paniagua-Martin MJ, Enriquez-Vazquez D, Vazquez-Rodriguez JM, Domenech N, Crespo-Leiro MG. Lopez-Vazquez P, et al. Among authors: fernandez caggiano m. Front Cardiovasc Med. 2024 Mar 8;11:1349417. doi: 10.3389/fcvm.2024.1349417. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38525191 Free PMC article.