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ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair.
Jimeno S, Prados-Carvajal R, Fernández-Ávila MJ, Silva S, Silvestris DA, Endara-Coll M, Rodríguez-Real G, Domingo-Prim J, Mejías-Navarro F, Romero-Franco A, Jimeno-González S, Barroso S, Cesarini V, Aguilera A, Gallo A, Visa N, Huertas P. Jimeno S, et al. Among authors: mejias navarro f. Nat Commun. 2021 Sep 17;12(1):5512. doi: 10.1038/s41467-021-25790-2. Nat Commun. 2021. PMID: 34535666 Free PMC article.
Controlling the balance between chromosome break repair pathways.
Jimeno S, Mejías-Navarro F, Prados-Carvajal R, Huertas P. Jimeno S, et al. Among authors: mejias navarro f. Adv Protein Chem Struct Biol. 2019;115:95-134. doi: 10.1016/bs.apcsb.2018.10.004. Epub 2018 Dec 5. Adv Protein Chem Struct Biol. 2019. PMID: 30798939 Review.
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.
López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, Mejías-Navarro F, Fernández-Ávila MJ, Dinant C, Martínez-Macías MI, Bartek J, Huertas P. López-Saavedra A, et al. Among authors: mejias navarro f. Nat Commun. 2016 Aug 9;7:12364. doi: 10.1038/ncomms12364. Nat Commun. 2016. PMID: 27503537 Free PMC article.