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Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome.
El Hindi K, Brachtendorf S, Hartel JC, Renné C, Birod K, Schilling K, Labocha S, Thomas D, Ferreirós N, Hahnefeld L, Dorochow E, Del Turco D, Deller T, Scholich K, Fuhrmann DC, Weigert A, Brüne B, Geisslinger G, Wittig I, Link KH, Grösch S. El Hindi K, et al. Among authors: ferreiros n. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166906. doi: 10.1016/j.bbadis.2023.166906. Epub 2023 Oct 4. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37802156 Free article.
Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells.
Wegner MS, Schömel N, Olzomer EM, Trautmann S, Olesch C, Byrne FL, Brüne B, Gurke R, Ferreirós N, Weigert A, Geisslinger G, Hoehn KL. Wegner MS, et al. Among authors: ferreiros n. Cell Mol Life Sci. 2021 Nov;78(21-22):7025-7041. doi: 10.1007/s00018-021-03958-9. Epub 2021 Oct 9. Cell Mol Life Sci. 2021. PMID: 34626204 Free PMC article.
Inhibitors of specific ceramide synthases.
Schiffmann S, Hartmann D, Fuchs S, Birod K, Ferreiròs N, Schreiber Y, Zivkovic A, Geisslinger G, Grösch S, Stark H. Schiffmann S, et al. Among authors: ferreiros n. Biochimie. 2012 Feb;94(2):558-65. doi: 10.1016/j.biochi.2011.09.007. Epub 2011 Sep 17. Biochimie. 2012. PMID: 21945810
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Pickert G, Lim HY, Weigert A, Häussler A, Myrczek T, Waldner M, Labocha S, Ferreirós N, Geisslinger G, Lötsch J, Becker C, Brüne B, Tegeder I. Pickert G, et al. Among authors: ferreiros n. Int J Cancer. 2013 Feb 1;132(3):591-604. doi: 10.1002/ijc.27706. Epub 2012 Jul 20. Int J Cancer. 2013. PMID: 22753274 Free article.
147 results