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A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Littler DR, Walker JR, Davis T, Wybenga-Groot LE, Finerty PJ Jr, Newman E, Mackenzie F, Dhe-Paganon S. Littler DR, et al. Among authors: finerty pj jr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1;66(Pt 2):143-51. doi: 10.1107/S1744309109052543. Epub 2010 Jan 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20124709 Free PMC article.
Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors.
Choi Y, Syeda F, Walker JR, Finerty PJ Jr, Cuerrier D, Wojciechowski A, Liu Q, Dhe-Paganon S, Gray NS. Choi Y, et al. Among authors: finerty pj jr. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70. doi: 10.1016/j.bmcl.2009.05.029. Epub 2009 May 13. Bioorg Med Chem Lett. 2009. PMID: 19553108 Free PMC article.
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.
Vedadi M, Niesen FH, Allali-Hassani A, Fedorov OY, Finerty PJ Jr, Wasney GA, Yeung R, Arrowsmith C, Ball LJ, Berglund H, Hui R, Marsden BD, Nordlund P, Sundstrom M, Weigelt J, Edwards AM. Vedadi M, et al. Among authors: finerty pj jr. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15835-40. doi: 10.1073/pnas.0605224103. Epub 2006 Oct 11. Proc Natl Acad Sci U S A. 2006. PMID: 17035505 Free PMC article.
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