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High-definition reconstruction of clonal composition in cancer.
Fischer A, Vázquez-García I, Illingworth CJR, Mustonen V. Fischer A, et al. Cell Rep. 2014 Jun 12;7(5):1740-1752. doi: 10.1016/j.celrep.2014.04.055. Epub 2014 May 29. Cell Rep. 2014. PMID: 24882004 Free PMC article.
Germline fitness-based scoring of cancer mutations.
Fischer A, Greenman C, Mustonen V. Fischer A, et al. Genetics. 2011 Jun;188(2):383-93. doi: 10.1534/genetics.111.127480. Epub 2011 Mar 24. Genetics. 2011. PMID: 21441214 Free PMC article.
The value of monitoring to control evolving populations.
Fischer A, Vázquez-García I, Mustonen V. Fischer A, et al. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1007-12. doi: 10.1073/pnas.1409403112. Epub 2015 Jan 13. Proc Natl Acad Sci U S A. 2015. PMID: 25587136 Free PMC article.
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P, Davies H, Jones D, Lin ML, Teague J, Bignell G, Butler A, Cho J, Dalgliesh GL, Galappaththige D, Greenman C, Hardy C, Jia M, Latimer C, Lau KW, Marshall J, McLaren S, Menzies A, Mudie L, Stebbings L, Largaespada DA, Wessels LF, Richard S, Kahnoski RJ, Anema J, Tuveson DA, Perez-Mancera PA, Mustonen V, Fischer A, Adams DJ, Rust A, Chan-on W, Subimerb C, Dykema K, Furge K, Campbell PJ, Teh BT, Stratton MR, Futreal PA. Varela I, et al. Among authors: fischer a. Nature. 2011 Jan 27;469(7331):539-42. doi: 10.1038/nature09639. Epub 2011 Jan 19. Nature. 2011. PMID: 21248752 Free PMC article.
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
Papaemmanuil E, Cazzola M, Boultwood J, Malcovati L, Vyas P, Bowen D, Pellagatti A, Wainscoat JS, Hellstrom-Lindberg E, Gambacorti-Passerini C, Godfrey AL, Rapado I, Cvejic A, Rance R, McGee C, Ellis P, Mudie LJ, Stephens PJ, McLaren S, Massie CE, Tarpey PS, Varela I, Nik-Zainal S, Davies HR, Shlien A, Jones D, Raine K, Hinton J, Butler AP, Teague JW, Baxter EJ, Score J, Galli A, Della Porta MG, Travaglino E, Groves M, Tauro S, Munshi NC, Anderson KC, El-Naggar A, Fischer A, Mustonen V, Warren AJ, Cross NC, Green AR, Futreal PA, Stratton MR, Campbell PJ; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. Papaemmanuil E, et al. Among authors: fischer a. N Engl J Med. 2011 Oct 13;365(15):1384-95. doi: 10.1056/NEJMoa1103283. Epub 2011 Sep 26. N Engl J Med. 2011. PMID: 21995386 Free PMC article.
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations.
Vázquez-García I, Salinas F, Li J, Fischer A, Barré B, Hallin J, Bergström A, Alonso-Perez E, Warringer J, Mustonen V, Liti G. Vázquez-García I, et al. Among authors: fischer a. Cell Rep. 2017 Oct 17;21(3):732-744. doi: 10.1016/j.celrep.2017.09.046. Cell Rep. 2017. PMID: 29045840 Free PMC article.
5,148 results