Flechsig E - Search Results

1

Immunisation strategies against prion diseases: prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie.

Nitschke C, Flechsig E, van den Brandt J, Lindner N, Lührs T, Dittmer U, Klein MA. Nitschke C, et al. Among authors: flechsig e. Vet Microbiol. 2007 Aug 31;123(4):367-76. doi: 10.1016/j.vetmic.2007.03.032. Epub 2007 Apr 5. Vet Microbiol. 2007. PMID: 17499458 Free article.

2

The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery.

Yun SW, Ertmer A, Flechsig E, Gilch S, Riederer P, Gerlach M, Schätzl HM, Klein MA. Yun SW, et al. Among authors: flechsig e. J Neurovirol. 2007 Aug;13(4):328-37. doi: 10.1080/13550280701361516. J Neurovirol. 2007. PMID: 17849316

3

Alteration of B-cell subsets enhances neuroinvasion in mouse scrapie infection.

von Poser-Klein C, Flechsig E, Hoffmann T, Schwarz P, Harms H, Bujdoso R, Aguzzi A, Klein MA. von Poser-Klein C, et al. Among authors: flechsig e. J Virol. 2008 Apr;82(7):3791-5. doi: 10.1128/JVI.02036-07. Epub 2008 Jan 16. J Virol. 2008. PMID: 18199638 Free PMC article.

4

Ultramicroscopy reveals axonal transport impairments in cortical motor neurons at prion disease.

Ermolayev V, Friedrich M, Nozadze R, Cathomen T, Klein MA, Harms GS, Flechsig E. Ermolayev V, et al. Among authors: flechsig e. Biophys J. 2009 Apr 22;96(8):3390-8. doi: 10.1016/j.bpj.2009.01.032. Biophys J. 2009. PMID: 19383482 Free PMC article.

5

The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells.

Ertmer A, Gilch S, Yun SW, Flechsig E, Klebl B, Stein-Gerlach M, Klein MA, Schätzl HM. Ertmer A, et al. Among authors: flechsig e. J Biol Chem. 2004 Oct 1;279(40):41918-27. doi: 10.1074/jbc.M405652200. Epub 2004 Jul 9. J Biol Chem. 2004. PMID: 15247213 Free article.

6

PrP expression in B lymphocytes is not required for prion neuroinvasion.

Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, Weissmann C, Aguzzi A. Klein MA, et al. Among authors: flechsig e. Nat Med. 1998 Dec;4(12):1429-33. doi: 10.1038/4022. Nat Med. 1998. PMID: 9846583

7

PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice.

Raeber AJ, Klein MA, Frigg R, Flechsig E, Aguzzi A, Weissmann C. Raeber AJ, et al. Among authors: flechsig e. EMBO J. 1999 May 17;18(10):2702-6. doi: 10.1093/emboj/18.10.2702. EMBO J. 1999. PMID: 10329617 Free PMC article.

8

Impaired axonal transport in motor neurons correlates with clinical prion disease.

Ermolayev V, Cathomen T, Merk J, Friedrich M, Härtig W, Harms GS, Klein MA, Flechsig E. Ermolayev V, et al. Among authors: flechsig e. PLoS Pathog. 2009 Aug;5(8):e1000558. doi: 10.1371/journal.ppat.1000558. Epub 2009 Aug 21. PLoS Pathog. 2009. PMID: 19696919 Free PMC article.

9

A crucial role for B cells in neuroinvasive scrapie.

Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, Aguzzi A. Klein MA, et al. Among authors: flechsig e. Nature. 1997 Dec 18-25;390(6661):687-90. doi: 10.1038/37789. Nature. 1997. PMID: 9414161

10

The role of PrP in health and disease.

Flechsig E, Weissmann C. Flechsig E, et al. Curr Mol Med. 2004 Jun;4(4):337-53. doi: 10.2174/1566524043360645. Curr Mol Med. 2004. PMID: 15354865 Review.

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