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Large-scale molecular epidemiological analysis of AAV in a cancer patient population.
Qin W, Xu G, Tai PWL, Wang C, Luo L, Li C, Hu X, Xue J, Lu Y, Zhou Q, Wei Q, Wen T, Hu J, Xiao Y, Yang L, Li W, Flotte TR, Wei Y, Gao G. Qin W, et al. Among authors: flotte tr. Oncogene. 2021 Apr;40(17):3060-3071. doi: 10.1038/s41388-021-01725-5. Epub 2021 Mar 29. Oncogene. 2021. PMID: 33782545 Free PMC article.
Preclinical study design for rAAV.
Flotte TR, Conlon TJ, Mueller C. Flotte TR, et al. Methods Mol Biol. 2011;807:317-37. doi: 10.1007/978-1-61779-370-7_14. Methods Mol Biol. 2011. PMID: 22034037
Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.
Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Among authors: flotte tr. Nat Methods. 2012 Mar 4;9(4):403-9. doi: 10.1038/nmeth.1903. Nat Methods. 2012. PMID: 22388288 Free PMC article.
Gene transfer in the lung using recombinant adeno-associated virus.
Gruntman AM, Mueller C, Flotte TR, Gao G. Gruntman AM, et al. Among authors: flotte tr. Curr Protoc Microbiol. 2012 Aug;Chapter 14:Unit14D.2. doi: 10.1002/9780471729259.mc14d02s26. Curr Protoc Microbiol. 2012. PMID: 22875566 Free PMC article.
A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.
Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, Matalon R, Gao G. Ahmed SS, et al. Among authors: flotte tr. Mol Ther. 2013 Dec;21(12):2136-47. doi: 10.1038/mt.2013.138. Epub 2013 Jul 2. Mol Ther. 2013. PMID: 23817205 Free PMC article.
314 results