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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S. Loft A, et al. Among authors: tsokanos ff. Cell Metab. 2022 Mar 1;34(3):473-486.e9. doi: 10.1016/j.cmet.2022.01.004. Epub 2022 Feb 3. Cell Metab. 2022. PMID: 35120589 Free article.
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.
Alfaro AJ, Dittner C, Becker J, Loft A, Mhamane A, Maida A, Georgiadi A, Tsokanos FF, Klepac K, Molocea CE, El-Merahbi R, Motzler K, Geppert J, Karikari RA, Szendrödi J, Feuchtinger A, Hofmann S, Karaca S, Urlaub H, Berriel Diaz M, Melchior F, Herzig S. Alfaro AJ, et al. Among authors: tsokanos ff. EMBO Rep. 2023 Oct 9;24(10):e55981. doi: 10.15252/embr.202255981. Epub 2023 Aug 10. EMBO Rep. 2023. PMID: 37560809 Free PMC article.
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
Bühler L, Maida A, Vogl ES, Georgiadi A, Takacs A, Kluth O, Schürmann A, Feuchtinger A, von Toerne C, Tsokanos FF, Klepac K, Wolff G, Sakurai M, Ekim Üstünel B, Nawroth P, Herzig S. Bühler L, et al. Among authors: tsokanos ff. Life Sci Alliance. 2021 Feb 3;4(4):e202000898. doi: 10.26508/lsa.202000898. Print 2021 Apr. Life Sci Alliance. 2021. PMID: 33536239 Free PMC article.
eIF4A inactivates TORC1 in response to amino acid starvation.
Tsokanos FF, Albert MA, Demetriades C, Spirohn K, Boutros M, Teleman AA. Tsokanos FF, et al. EMBO J. 2016 May 17;35(10):1058-76. doi: 10.15252/embj.201593118. Epub 2016 Mar 17. EMBO J. 2016. PMID: 26988032 Free PMC article.
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Blüher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. Giroud M, et al. Among authors: tsokanos ff. Diabetologia. 2021 Aug;64(8):1850-1865. doi: 10.1007/s00125-021-05470-y. Epub 2021 May 20. Diabetologia. 2021. PMID: 34014371 Free PMC article.
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.
Hartleben G, Schorpp K, Kwon Y, Betz B, Tsokanos FF, Dantes Z, Schäfer A, Rothenaigner I, Monroy Kuhn JM, Morigny P, Mehr L, Lin S, Seitz S, Tokarz J, Artati A, Adamsky J, Plettenburg O, Lutter D, Irmler M, Beckers J, Reichert M, Hadian K, Zeigerer A, Herzig S, Berriel Diaz M. Hartleben G, et al. Among authors: tsokanos ff. EMBO Mol Med. 2021 Apr 9;13(4):e12461. doi: 10.15252/emmm.202012461. Epub 2021 Mar 5. EMBO Mol Med. 2021. PMID: 33665961 Free PMC article.
Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.
Morigny P, Kaltenecker D, Zuber J, Machado J, Mehr L, Tsokanos FF, Kuzi H, Hermann CD, Voelkl M, Monogarov G, Springfeld C, Laurent V, Engelmann B, Friess H, Zörnig I, Krüger A, Krijgsveld J, Prokopchuk O, Fisker Schmidt S, Rohm M, Herzig S, Berriel Diaz M. Morigny P, et al. Among authors: tsokanos ff. J Cachexia Sarcopenia Muscle. 2021 Oct;12(5):1333-1351. doi: 10.1002/jcsm.12758. Epub 2021 Aug 23. J Cachexia Sarcopenia Muscle. 2021. PMID: 34427055 Free PMC article.