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Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition.
Sunshine SB, Dallabrida SM, Durand E, Ismail NS, Bazinet L, Birsner AE, Sohn R, Ikeda S, Pu WT, Kulke MH, Javaherian K, Zurakowski D, Folkman JM, Rupnick M. Sunshine SB, et al. Among authors: folkman jm. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11306-11. doi: 10.1073/pnas.1203275109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733742 Free PMC article.
Endostatin therapy reveals a U-shaped curve for antitumor activity.
Tjin Tham Sjin RM, Naspinski J, Birsner AE, Li C, Chan R, Lo KM, Gillies S, Zurakowski D, Folkman J, Samulski J, Javaherian K. Tjin Tham Sjin RM, et al. Among authors: folkman j. Cancer Gene Ther. 2006 Jun;13(6):619-27. doi: 10.1038/sj.cgt.7700938. Cancer Gene Ther. 2006. PMID: 16456550
466 results