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1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors.
Micheli F, Cavanni P, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Checchia A, Davalli S, Di Fabio R, Fazzolari E, Fontana S, Marchioro C, Minick D, Negri M, Oliosi B, Read KD, Sartori I, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L. Micheli F, et al. Among authors: fontana s. J Med Chem. 2010 Mar 25;53(6):2534-51. doi: 10.1021/jm901818u. J Med Chem. 2010. PMID: 20170186
1,2,4-Triazolyl azabicyclo[3.1.0]hexanes: a new series of potent and selective dopamine D(3) receptor antagonists.
Micheli F, Arista L, Bonanomi G, Blaney FE, Braggio S, Capelli AM, Checchia A, Damiani F, Di-Fabio R, Fontana S, Gentile G, Griffante C, Hamprecht D, Marchioro C, Mugnaini M, Piner J, Ratti E, Tedesco G, Tarsi L, Terreni S, Worby A, Ashby CR Jr, Heidbreder C. Micheli F, et al. Among authors: fontana s. J Med Chem. 2010 Jan 14;53(1):374-91. doi: 10.1021/jm901319p. J Med Chem. 2010. PMID: 19891474
6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.
Micheli F, Cavanni P, Andreotti D, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Carletti R, Checchia A, Corsi M, Fazzolari E, Fontana S, Marchioro C, Merlo-Pich E, Negri M, Oliosi B, Ratti E, Read KD, Roscic M, Sartori I, Spada S, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L, Di Fabio R. Micheli F, et al. Among authors: fontana s. J Med Chem. 2010 Jul 8;53(13):4989-5001. doi: 10.1021/jm100481d. J Med Chem. 2010. PMID: 20527970
Design and synthesis of novel tricyclic benzoxazines as potent 5-HT(1A/B/D) receptor antagonists leading to the discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045).
Bromidge SM, Arban R, Bertani B, Bison S, Borriello M, Cavanni P, Dal Forno G, Di-Fabio R, Donati D, Fontana S, Gianotti M, Gordon LJ, Granci E, Leslie CP, Moccia L, Pasquarello A, Sartori I, Sava A, Watson JM, Worby A, Zonzini L, Zucchelli V. Bromidge SM, et al. Among authors: fontana s. J Med Chem. 2010 Aug 12;53(15):5827-43. doi: 10.1021/jm100482n. J Med Chem. 2010. PMID: 20590088
Development and validation of a high-throughput method for the quantitative analysis of D-amphetamine in rat blood using liquid chromatography/MS3 on a hybrid triple quadrupole-linear ion trap mass spectrometer and its application to a pharmacokinetic study.
Cesari N, Fontana S, Montanari D, Braggio S. Cesari N, et al. Among authors: fontana s. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jan 1;878(1):21-8. doi: 10.1016/j.jchromb.2009.11.009. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 19945359
Acylglycinamides as inhibitors of glycine transporter type 1.
Blunt R, Porter R, Johns A, Nash D, Puckey G, Wyman P, Herdon H, Teague S, Hadden V, Fontana S, Gordon L. Blunt R, et al. Among authors: fontana s. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6176-9. doi: 10.1016/j.bmcl.2011.07.096. Epub 2011 Aug 6. Bioorg Med Chem Lett. 2011. PMID: 21889344
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor.
Del Bello F, Bonifazi A, Giorgioni G, Cifani C, Micioni Di Bonaventura MV, Petrelli R, Piergentili A, Fontana S, Mammoli V, Yano H, Matucci R, Vistoli G, Quaglia W. Del Bello F, et al. Among authors: fontana s. J Med Chem. 2018 Apr 26;61(8):3712-3725. doi: 10.1021/acs.jmedchem.8b00265. Epub 2018 Apr 6. J Med Chem. 2018. PMID: 29589445
404 results