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Ferroptosis regulation by the NGLY1/NFE2L1 pathway.
Forcina GC, Pope L, Murray M, Dong W, Abu-Remaileh M, Bertozzi CR, Dixon SJ. Forcina GC, et al. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2118646119. doi: 10.1073/pnas.2118646119. Epub 2022 Mar 10. Proc Natl Acad Sci U S A. 2022. PMID: 35271393 Free PMC article.
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.
Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ. Magtanong L, et al. Among authors: forcina gc. Cell Chem Biol. 2019 Mar 21;26(3):420-432.e9. doi: 10.1016/j.chembiol.2018.11.016. Epub 2019 Jan 24. Cell Chem Biol. 2019. PMID: 30686757 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: forcina gc. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
Kinetic Heterogeneity of Cancer Cell Fractional Killing.
Inde Z, Forcina GC, Denton K, Dixon SJ. Inde Z, et al. Among authors: forcina gc. Cell Rep. 2020 Jul 7;32(1):107845. doi: 10.1016/j.celrep.2020.107845. Cell Rep. 2020. PMID: 32640215 Free PMC article.
A compendium of kinetic modulatory profiles identifies ferroptosis regulators.
Conlon M, Poltorack CD, Forcina GC, Armenta DA, Mallais M, Perez MA, Wells A, Kahanu A, Magtanong L, Watts JL, Pratt DA, Dixon SJ. Conlon M, et al. Among authors: forcina gc. Nat Chem Biol. 2021 Jun;17(6):665-674. doi: 10.1038/s41589-021-00751-4. Epub 2021 Mar 8. Nat Chem Biol. 2021. PMID: 33686292 Free PMC article.
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
Johnson FD, Ferrarone J, Liu A, Brandstädter C, Munuganti R, Farnsworth DA, Lu D, Luu J, Sihota T, Jansen S, Nagelberg A, Shi R, Forcina GC, Zhang X, Cheng GSW, Spencer Miko SE, de Rappard-Yuswack G, Sorensen PH, Dixon SJ, Guha U, Becker K, Djaballah H, Somwar R, Varmus H, Morin GB, Lockwood WW. Johnson FD, et al. Among authors: forcina gc. Cell Rep. 2022 Feb 8;38(6):110343. doi: 10.1016/j.celrep.2022.110343. Cell Rep. 2022. PMID: 35139387 Free PMC article.