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Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Yoo TH, Pedigo CE, Guzman J, Correa-Medina M, Wei C, Villarreal R, Mitrofanova A, Leclercq F, Faul C, Li J, Kretzler M, Nelson RG, Lehto M, Forsblom C, Groop PH, Reiser J, Burke GW, Fornoni A, Merscher S. Yoo TH, et al. Among authors: fornoni a. J Am Soc Nephrol. 2015 Jan;26(1):133-47. doi: 10.1681/ASN.2013111213. Epub 2014 Jun 12. J Am Soc Nephrol. 2015. PMID: 24925721 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes.
Ahmad A, Mitrofanova A, Bielawski J, Yang Y, Marples B, Fornoni A, Zeidan YH. Ahmad A, et al. Among authors: fornoni a. FASEB J. 2017 Feb;31(2):771-780. doi: 10.1096/fj.201600618R. Epub 2016 Nov 11. FASEB J. 2017. PMID: 27836988 Free PMC article.
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a known off target of the anti-CD20 antibody rituximab (RTX). ...-Ahmad, A., Mitrofanova, A., Bielawski, J., Yang, Y., Marple …
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a …
Translational Aspects of Sphingolipid Metabolism in Renal Disorders.
Abou Daher A, El Jalkh T, Eid AA, Fornoni A, Marples B, Zeidan YH. Abou Daher A, et al. Among authors: fornoni a. Int J Mol Sci. 2017 Nov 25;18(12):2528. doi: 10.3390/ijms18122528. Int J Mol Sci. 2017. PMID: 29186855 Free PMC article. Review.
SMPDL3b modulates insulin receptor signaling in diabetic kidney disease.
Mitrofanova A, Mallela SK, Ducasa GM, Yoo TH, Rosenfeld-Gur E, Zelnik ID, Molina J, Varona Santos J, Ge M, Sloan A, Kim JJ, Pedigo C, Bryn J, Volosenco I, Faul C, Zeidan YH, Garcia Hernandez C, Mendez AJ, Leibiger I, Burke GW, Futerman AH, Barisoni L, Ishimoto Y, Inagi R, Merscher S, Fornoni A. Mitrofanova A, et al. Among authors: fornoni a. Nat Commun. 2019 Jun 19;10(1):2692. doi: 10.1038/s41467-019-10584-4. Nat Commun. 2019. PMID: 31217420 Free PMC article.
Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome.
Kim JJ, David JM, Wilbon SS, Santos JV, Patel DM, Ahmad A, Mitrofanova A, Liu X, Mallela SK, Ducasa GM, Ge M, Sloan AJ, Al-Ali H, Boulina M, Mendez AJ, Contreras GN, Prunotto M, Sohail A, Fridman R, Miner JH, Merscher S, Fornoni A. Kim JJ, et al. Among authors: fornoni a. EBioMedicine. 2021 Jan;63:103162. doi: 10.1016/j.ebiom.2020.103162. Epub 2020 Dec 16. EBioMedicine. 2021. PMID: 33340991 Free PMC article.
Noninvasive assessment of radiation-induced renal injury in mice.
Ahmad A, Shi J, Ansari S, Afaghani J, Molina J, Pollack A, Merscher S, Zeidan YH, Fornoni A, Marples B. Ahmad A, et al. Among authors: fornoni a. Int J Radiat Biol. 2021;97(5):664-674. doi: 10.1080/09553002.2021.1876950. Epub 2021 Mar 15. Int J Radiat Biol. 2021. PMID: 33464992 Free PMC article.
Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Wright MB, Varona Santos J, Kemmer C, Maugeais C, Carralot JP, Roever S, Molina J, Ducasa GM, Mitrofanova A, Sloan A, Ahmad A, Pedigo C, Ge M, Pressly J, Barisoni L, Mendez A, Sgrignani J, Cavalli A, Merscher S, Prunotto M, Fornoni A. Wright MB, et al. Among authors: fornoni a. Nat Commun. 2021 Aug 2;12(1):4662. doi: 10.1038/s41467-021-24890-3. Nat Commun. 2021. PMID: 34341345 Free PMC article.
213 results