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Page 1
Epac Function and cAMP Scaffolds in the Heart and Lung.
Laudette M, Zuo H, Lezoualc'h F, Schmidt M. Laudette M, et al. Among authors: lezoualc h f. J Cardiovasc Dev Dis. 2018 Feb 3;5(1):9. doi: 10.3390/jcdd5010009. J Cardiovasc Dev Dis. 2018. PMID: 29401660 Free PMC article. Review.
Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death.
Fazal L, Laudette M, Paula-Gomes S, Pons S, Conte C, Tortosa F, Sicard P, Sainte-Marie Y, Bisserier M, Lairez O, Lucas A, Roy J, Ghaleh B, Fauconnier J, Mialet-Perez J, Lezoualc'h F. Fazal L, et al. Among authors: lezoualc h f. Circ Res. 2017 Feb 17;120(4):645-657. doi: 10.1161/CIRCRESAHA.116.309859. Epub 2017 Jan 17. Circ Res. 2017. PMID: 28096195 Free article.
Cyclic AMP-binding protein Epac1 acts as a metabolic sensor to promote cardiomyocyte lipotoxicity.
Laudette M, Sainte-Marie Y, Cousin G, Bergonnier D, Belhabib I, Brun S, Formoso K, Laib L, Tortosa F, Bergoglio C, Marcheix B, Borén J, Lairez O, Fauconnier J, Lucas A, Mialet-Perez J, Moro C, Lezoualc'h F. Laudette M, et al. Among authors: lezoualc h f. Cell Death Dis. 2021 Sep 1;12(9):824. doi: 10.1038/s41419-021-04113-9. Cell Death Dis. 2021. PMID: 34471096 Free PMC article.
Metformin protects against diclofenac-induced toxicity in primary rat hepatocytes by preserving mitochondrial integrity via a pathway involving EPAC.
Mora FAA, Musheshe N, Arroyave Ospina JC, Geng Y, Soto JM, Rodrigo JA, Alieva T, Buist-Homan M, Lezoualc'h F, Cheng X, Schmidt M, Moshage H. Mora FAA, et al. Among authors: lezoualc h f. Biomed Pharmacother. 2021 Nov;143:112072. doi: 10.1016/j.biopha.2021.112072. Epub 2021 Aug 28. Biomed Pharmacother. 2021. PMID: 34464747 Free article.
Carabin protects against cardiac hypertrophy by blocking calcineurin, Ras, and Ca2+/calmodulin-dependent protein kinase II signaling.
Bisserier M, Berthouze-Duquesnes M, Breckler M, Tortosa F, Fazal L, de Régibus A, Laurent AC, Varin A, Lucas A, Branchereau M, Marck P, Schickel JN, Deloménie C, Cazorla O, Soulas-Sprauel P, Crozatier B, Morel E, Heymes C, Lezoualc'h F. Bisserier M, et al. Among authors: lezoualc h f. Circulation. 2015 Jan 27;131(4):390-400; discussion 400. doi: 10.1161/CIRCULATIONAHA.114.010686. Epub 2014 Nov 4. Circulation. 2015. PMID: 25369805