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Page 1
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Life Sci Alliance. 2022 Jan 21;5(4):e202101187. doi: 10.26508/lsa.202101187. Print 2022 Apr.
Life Sci Alliance. 2022.
PMID: 35064075
Free PMC article.
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat J, Heuberger J, Vidal RO, Goveas N, Kosel F, Berenguer-Llergo A, Kranz A, Wulf-Goldenberg A, Behrens D, Melcher B, Sauer S, Vieth M, Batlle E, Stewart AF, Birchmeier W.
Grinat J, et al. Among authors: kosel f.
Nat Commun. 2020 Dec 21;11(1):6422. doi: 10.1038/s41467-020-20222-z.
Nat Commun. 2020.
PMID: 33349639
Free PMC article.
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High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W.
Heuberger J, et al. Among authors: kosel f.
Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2019699118. doi: 10.1073/pnas.2019699118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34039707
Free PMC article.
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Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger J, Kosel F, Qi J, Grossmann KS, Rajewsky K, Birchmeier W.
Heuberger J, et al. Among authors: kosel f.
Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3472-7. doi: 10.1073/pnas.1309342111. Epub 2014 Feb 18.
Proc Natl Acad Sci U S A. 2014.
PMID: 24550486
Free PMC article.
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Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
Wend P, Fang L, Zhu Q, Schipper JH, Loddenkemper C, Kosel F, Brinkmann V, Eckert K, Hindersin S, Holland JD, Lehr S, Kahn M, Ziebold U, Birchmeier W.
Wend P, et al. Among authors: kosel f.
EMBO J. 2013 Jul 17;32(14):1977-89. doi: 10.1038/emboj.2013.127. Epub 2013 Jun 4.
EMBO J. 2013.
PMID: 23736260
Free PMC article.
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A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann J, Morkel M, Besser D, Budczies J, Kosel F, Brembeck FH, Stein U, Fichtner I, Schlag PM, Birchmeier W.
Fritzmann J, et al. Among authors: kosel f.
Gastroenterology. 2009 Jul;137(1):165-75. doi: 10.1053/j.gastro.2009.03.041. Epub 2009 Mar 26.
Gastroenterology. 2009.
PMID: 19328798
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