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Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV.
Bergmann JF, de Bruijne J, Hotho DM, de Knegt RJ, Boonstra A, Weegink CJ, van Vliet AA, van de Wetering J, Fletcher SP, Bauman LA, Rahimy M, Appleman JR, Freddo JL, Janssen HL, Reesink HW. Bergmann JF, et al. Among authors: freddo jl. Aliment Pharmacol Ther. 2011 Aug;34(4):443-53. doi: 10.1111/j.1365-2036.2011.04745.x. Epub 2011 Jun 26. Aliment Pharmacol Ther. 2011. PMID: 21707679 Free article. Clinical Trial.
Potent immune activation in chronic hepatitis C patients upon administration of an oral inducer of endogenous interferons that acts via Toll-like receptor 7.
Boonstra A, Liu BS, Groothuismink ZM, Bergmann JF, de Bruijne J, Hotho DM, Hansen BE, van Vliet AA, van de Wetering de Rooij J, Fletcher SP, Bauman LA, Rahimy M, Appleman JR, Freddo JL, Reesink HW, de Knegt RJ, Janssen HL. Boonstra A, et al. Among authors: freddo jl. Antivir Ther. 2012;17(4):657-67. doi: 10.3851/IMP2023. Epub 2011 Dec 19. Antivir Ther. 2012. PMID: 22301364
Phase I trial of cisplatin in combination with glutathione.
Plaxe S, Freddo J, Kim S, Kirmani S, McClay E, Christen R, Braly P, Howell S. Plaxe S, et al. Gynecol Oncol. 1994 Oct;55(1):82-6. doi: 10.1006/gyno.1994.1252. Gynecol Oncol. 1994. PMID: 7959273 Clinical Trial.
Phase I and pharmacokinetic study of intraperitoneal ormaplatin.
Plaxe SC, Braly PS, Freddo JL, McClay E, Christen RD, Kirmani S, Kim S, Heath D, Howell SB. Plaxe SC, et al. Among authors: freddo jl. Gynecol Oncol. 1993 Oct;51(1):72-7. doi: 10.1006/gyno.1993.1249. Gynecol Oncol. 1993. PMID: 8244179 Clinical Trial.
Phase I/pharmacokinetic study of high-dose progesterone and doxorubicin.
Christen RD, McClay EF, Plaxe SC, Yen SS, Kim S, Kirmani S, Wilgus LL, Heath DD, Shalinsky DR, Freddo JL, et al. Christen RD, et al. Among authors: freddo jl. J Clin Oncol. 1993 Dec;11(12):2417-26. doi: 10.1200/JCO.1993.11.12.2417. J Clin Oncol. 1993. PMID: 8246031 Clinical Trial.
Phase I and pharmacokinetic study of intraperitoneal topotecan.
Plaxe SC, Christen RD, O'Quigley J, Braly PS, Freddo JL, McClay E, Heath D, Howell SB. Plaxe SC, et al. Among authors: freddo jl. Invest New Drugs. 1998;16(2):147-53. doi: 10.1023/a:1006045125018. Invest New Drugs. 1998. PMID: 9848578 Clinical Trial.
13 results