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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 1
1981 1
1983 1
1986 1
1987 1
1988 1
1989 4
1991 4
1992 9
1993 12
1994 11
1995 9
1996 9
1997 13
1998 7
1999 7
2000 6
2001 8
2002 9
2003 9
2004 7
2005 8
2006 12
2007 18
2008 19
2009 16
2010 16
2011 12
2012 8
2013 21
2014 16
2015 29
2016 32
2017 23
2018 23
2019 20
2020 18
2021 19
2022 19
2023 17
2024 4

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443 results

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Page 1
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R. Hashimoto M, et al. Among authors: freeman gj. Nature. 2022 Oct;610(7930):173-181. doi: 10.1038/s41586-022-05257-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171288 Free PMC article.
PD-1 and its ligands in tolerance and immunity.
Keir ME, Butte MJ, Freeman GJ, Sharpe AH. Keir ME, et al. Among authors: freeman gj. Annu Rev Immunol. 2008;26:677-704. doi: 10.1146/annurev.immunol.26.021607.090331. Annu Rev Immunol. 2008. PMID: 18173375 Free PMC article. Review.
Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.
Park JS, Gazzaniga FS, Wu M, Luthens AK, Gillis J, Zheng W, LaFleur MW, Johnson SB, Morad G, Park EM, Zhou Y, Watowich SS, Wargo JA, Freeman GJ, Kasper DL, Sharpe AH. Park JS, et al. Among authors: freeman gj. Nature. 2023 May;617(7960):377-385. doi: 10.1038/s41586-023-06026-3. Epub 2023 May 3. Nature. 2023. PMID: 37138075 Free PMC article.
PI3Kβ controls immune evasion in PTEN-deficient breast tumours.
Bergholz JS, Wang Q, Wang Q, Ramseier M, Prakadan S, Wang W, Fang R, Kabraji S, Zhou Q, Gray GK, Abell-Hart K, Xie S, Guo X, Gu H, Von T, Jiang T, Tang S, Freeman GJ, Kim HJ, Shalek AK, Roberts TM, Zhao JJ. Bergholz JS, et al. Among authors: freeman gj. Nature. 2023 May;617(7959):139-146. doi: 10.1038/s41586-023-05940-w. Epub 2023 Apr 19. Nature. 2023. PMID: 37076617
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.
Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, Gokhale PC, Gonzalez Castro LN, Shore ME, Hebert CM, Shaw B, Cahill HL, Drummond M, Zhang W, Olawoyin O, Wakimoto H, Rozenblatt-Rosen O, Brastianos PK, Liu XS, Jones PS, Cahill DP, Frosch MP, Louis DN, Freeman GJ, Ligon KL, Marson A, Chiocca EA, Reardon DA, Regev A, Suvà ML, Wucherpfennig KW. Mathewson ND, et al. Among authors: freeman gj. Cell. 2021 Mar 4;184(5):1281-1298.e26. doi: 10.1016/j.cell.2021.01.022. Epub 2021 Feb 15. Cell. 2021. PMID: 33592174 Free PMC article.
USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy.
Xiong W, Gao X, Zhang T, Jiang B, Hu MM, Bu X, Gao Y, Zhang LZ, Xiao BL, He C, Sun Y, Li H, Shi J, Xiao X, Xiang B, Xie C, Chen G, Zhang H, Wei W, Freeman GJ, Shu HB, Wang H, Zhang J. Xiong W, et al. Among authors: freeman gj. Nat Commun. 2022 Mar 31;13(1):1700. doi: 10.1038/s41467-022-29401-6. Nat Commun. 2022. PMID: 35361799 Free PMC article.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J. Xiao X, et al. Among authors: freeman gj. Nat Commun. 2023 May 19;14(1):2859. doi: 10.1038/s41467-023-38605-3. Nat Commun. 2023. PMID: 37208329 Free PMC article.
Emerging concepts in PD-1 checkpoint biology.
Pauken KE, Torchia JA, Chaudhri A, Sharpe AH, Freeman GJ. Pauken KE, et al. Among authors: freeman gj. Semin Immunol. 2021 Feb;52:101480. doi: 10.1016/j.smim.2021.101480. Epub 2021 May 15. Semin Immunol. 2021. PMID: 34006473 Free PMC article. Review.
443 results