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Crosstalk between mechanotransduction and metabolism.
Romani P, Valcarcel-Jimenez L, Frezza C, Dupont S. Romani P, et al. Among authors: frezza c. Nat Rev Mol Cell Biol. 2021 Jan;22(1):22-38. doi: 10.1038/s41580-020-00306-w. Epub 2020 Nov 13. Nat Rev Mol Cell Biol. 2021. PMID: 33188273 Review.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Among authors: frezza c. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
Mitochondrial Metabolism: Yin and Yang for Tumor Progression.
Valcarcel-Jimenez L, Gaude E, Torrano V, Frezza C, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: frezza c. Trends Endocrinol Metab. 2017 Oct;28(10):748-757. doi: 10.1016/j.tem.2017.06.004. Trends Endocrinol Metab. 2017. PMID: 28938972 Free PMC article. Review.
Metabolism and cancer: the future is now.
Frezza C. Frezza C. Br J Cancer. 2020 Jan;122(2):133-135. doi: 10.1038/s41416-019-0667-3. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819199 Free PMC article.
Cancer associated fibroblast FAK regulates malignant cell metabolism.
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J, Newport E, Rajeeve V, Baker AM, Roy-Luzarraga M, Graham TA, Foster J, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Balkwill FR, Sosabowski J, Cutillas PR, Frezza C, Sancho P, Hodivala-Dilke K. Demircioglu F, et al. Among authors: frezza c. Nat Commun. 2020 Mar 10;11(1):1290. doi: 10.1038/s41467-020-15104-3. Nat Commun. 2020. PMID: 32157087 Free PMC article.
HIRA loss transforms FH-deficient cells.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Valcarcel-Jimenez L, et al. Among authors: frezza c. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269833 Free PMC article.
Fumarate hydratase (FH) and cancer: a paradigm of oncometabolism.
Valcarcel-Jimenez L, Frezza C. Valcarcel-Jimenez L, et al. Among authors: frezza c. Br J Cancer. 2023 Nov;129(10):1546-1557. doi: 10.1038/s41416-023-02412-w. Epub 2023 Sep 9. Br J Cancer. 2023. PMID: 37689804 Free PMC article. Review.
232 results