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Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH, Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S. Rudolph V, et al. Nat Med. 2010 Apr;16(4):470-4. doi: 10.1038/nm.2124. Epub 2010 Mar 21. Nat Med. 2010. PMID: 20305660 Free PMC article.
Myeloperoxidase attracts neutrophils by physical forces.
Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S. Klinke A, et al. Blood. 2011 Jan 27;117(4):1350-8. doi: 10.1182/blood-2010-05-284513. Epub 2010 Oct 27. Blood. 2011. PMID: 20980678 Free article.
Myeloperoxidase deficiency preserves vasomotor function in humans.
Rudolph TK, Wipper S, Reiter B, Rudolph V, Coym A, Detter C, Lau D, Klinke A, Friedrichs K, Rau T, Pekarova M, Russ D, Knöll K, Kolk M, Schroeder B, Wegscheider K, Andresen H, Schwedhelm E, Boeger R, Ehmke H, Baldus S. Rudolph TK, et al. Eur Heart J. 2012 Jul;33(13):1625-34. doi: 10.1093/eurheartj/ehr193. Epub 2011 Jun 30. Eur Heart J. 2012. PMID: 21724624 Free PMC article.
Inflammatory pathways underlying atrial fibrillation.
Friedrichs K, Klinke A, Baldus S. Friedrichs K, et al. Trends Mol Med. 2011 Oct;17(10):556-63. doi: 10.1016/j.molmed.2011.05.007. Epub 2011 Jul 15. Trends Mol Med. 2011. PMID: 21763201 Review.
Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension.
Klinke A, Möller A, Pekarova M, Ravekes T, Friedrichs K, Berlin M, Scheu KM, Kubala L, Kolarova H, Ambrozova G, Schermuly RT, Woodcock SR, Freeman BA, Rosenkranz S, Baldus S, Rudolph V, Rudolph TK. Klinke A, et al. Am J Respir Cell Mol Biol. 2014 Jul;51(1):155-62. doi: 10.1165/rcmb.2013-0063OC. Am J Respir Cell Mol Biol. 2014. PMID: 24521348 Free PMC article.
Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins.
Friedrichs K, Adam M, Remane L, Mollenhauer M, Rudolph V, Rudolph TK, Andrié RP, Stöckigt F, Schrickel JW, Ravekes T, Deuschl F, Nickenig G, Willems S, Baldus S, Klinke A. Friedrichs K, et al. PLoS One. 2014 Feb 18;9(2):e89307. doi: 10.1371/journal.pone.0089307. eCollection 2014. PLoS One. 2014. PMID: 24558493 Free PMC article.
60 results