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Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B. Kaupmann K, et al. Among authors: froestl w. Eur J Neurosci. 2003 Nov;18(10):2722-30. doi: 10.1111/j.1460-9568.2003.03013.x. Eur J Neurosci. 2003. PMID: 14656321
Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines.
Cryan JF, Kelly PH, Chaperon F, Gentsch C, Mombereau C, Lingenhoehl K, Froestl W, Bettler B, Kaupmann K, Spooren WP. Cryan JF, et al. Among authors: froestl w. J Pharmacol Exp Ther. 2004 Sep;310(3):952-63. doi: 10.1124/jpet.104.066753. Epub 2004 Apr 27. J Pharmacol Exp Ther. 2004. PMID: 15113848
N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.
Urwyler S, Pozza MF, Lingenhoehl K, Mosbacher J, Lampert C, Froestl W, Koller M, Kaupmann K. Urwyler S, et al. Among authors: froestl w. J Pharmacol Exp Ther. 2003 Oct;307(1):322-30. doi: 10.1124/jpet.103.053074. Epub 2003 Sep 3. J Pharmacol Exp Ther. 2003. PMID: 12954816
Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.
Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, Gentry C, Jaton AL, Van der Putten H, Mombereau C, Lecourtier L, Mosbacher J, Cryan JF, Fritschy JM, Lüthi A, Kaupmann K, Bettler B. Gassmann M, et al. Among authors: froestl w. J Neurosci. 2004 Jul 7;24(27):6086-97. doi: 10.1523/JNEUROSCI.5635-03.2004. J Neurosci. 2004. PMID: 15240800 Free PMC article.
Ligands for the isolation of GABA(B) receptors [corrected].
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Froestl W, et al. Neuropharmacology. 1999 Nov;38(11):1641-6. doi: 10.1016/s0028-3908(99)00134-3. Neuropharmacology. 1999. PMID: 10587079 Review.
Ligands for expression cloning and isolation of GABA(B) receptors.
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Froestl W, et al. Farmaco. 2001 Jan-Feb;56(1-2):101-5. doi: 10.1016/s0014-827x(01)01003-5. Farmaco. 2001. PMID: 11347948 Review.
In order to isolate the extracellular domain(s) of GABA(B) receptors 1a (or 1b) and to purify and crystallise these proteins a third ligand [125I]CGP84963 was designed, which combines, in one molecule, a GABA(B) receptor binding part, an azidosalicylic acid as photoaffinity moiet …
In order to isolate the extracellular domain(s) of GABA(B) receptors 1a (or 1b) and to purify and crystallise these proteins a third ligand …
88 results