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Polycomb target genes are silenced in multiple myeloma.
Kalushkova A, Fryknäs M, Lemaire M, Fristedt C, Agarwal P, Eriksson M, Deleu S, Atadja P, Osterborg A, Nilsson K, Vanderkerken K, Oberg F, Jernberg-Wiklund H. Kalushkova A, et al. Among authors: fryknas m. PLoS One. 2010 Jul 9;5(7):e11483. doi: 10.1371/journal.pone.0011483. PLoS One. 2010. PMID: 20634887 Free PMC article.
AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and dose dependent reduction of tyrosine kinase activity in acute myeloid leukemia.
Eriksson A, Kalushkova A, Jarvius M, Hilhorst R, Rickardson L, Kultima HG, de Wijn R, Hovestad L, Fryknäs M, Öberg F, Larsson R, Parrow V, Höglund M. Eriksson A, et al. Among authors: fryknas m. Biochem Pharmacol. 2014 Jan 15;87(2):284-91. doi: 10.1016/j.bcp.2013.10.022. Epub 2013 Nov 4. Biochem Pharmacol. 2014. PMID: 24200998 Free article. Clinical Trial.
Ex vivo activity of cardiac glycosides in acute leukaemia.
Hallböök H, Felth J, Eriksson A, Fryknäs M, Bohlin L, Larsson R, Gullbo J. Hallböök H, et al. Among authors: fryknas m. PLoS One. 2011 Jan 5;6(1):e15718. doi: 10.1371/journal.pone.0015718. PLoS One. 2011. PMID: 21246039 Free PMC article.
Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment.
Gullbo J, Fryknäs M, Rickardson L, Darcy P, Hägg M, Wickström M, Hassan S, Westman G, Brnjic S, Nygren P, Linder S, Larsson R. Gullbo J, et al. Among authors: fryknas m. Biochem Pharmacol. 2011 Jul 15;82(2):139-47. doi: 10.1016/j.bcp.2011.04.003. Epub 2011 Apr 22. Biochem Pharmacol. 2011. PMID: 21531212 Free article.
The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Hernlund E, Olofsson MH, Fayad W, Fryknäs M, Lesiak-Mieczkowska K, Zhang X, Brnjic S, Schmidt V, D'Arcy P, Sjöblom T, De Milito A, Larsson R, Linder S. Hernlund E, et al. Among authors: fryknas m. Eur J Cancer. 2012 Feb;48(3):396-406. doi: 10.1016/j.ejca.2011.11.013. Epub 2011 Dec 7. Eur J Cancer. 2012. PMID: 22154651
71 results