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Ferroptosis of tumour neutrophils causes immune suppression in cancer.
Kim R, Hashimoto A, Markosyan N, Tyurin VA, Tyurina YY, Kar G, Fu S, Sehgal M, Garcia-Gerique L, Kossenkov A, Gebregziabher BA, Tobias JW, Hicks K, Halpin RA, Cvetesic N, Deng H, Donthireddy L, Greenberg A, Nam B, Vonderheide RH, Nefedova Y, Kagan VE, Gabrilovich DI. Kim R, et al. Among authors: fu s. Nature. 2022 Dec;612(7939):338-346. doi: 10.1038/s41586-022-05443-0. Epub 2022 Nov 16. Nature. 2022. PMID: 36385526 Free PMC article.
Unique pattern of neutrophil migration and function during tumor progression.
Patel S, Fu S, Mastio J, Dominguez GA, Purohit A, Kossenkov A, Lin C, Alicea-Torres K, Sehgal M, Nefedova Y, Zhou J, Languino LR, Clendenin C, Vonderheide RH, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Schug ZT, Altieri DC, Gabrilovich DI. Patel S, et al. Among authors: fu s. Nat Immunol. 2018 Nov;19(11):1236-1247. doi: 10.1038/s41590-018-0229-5. Epub 2018 Oct 15. Nat Immunol. 2018. PMID: 30323345 Free PMC article.
Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs.
Mastio J, Condamine T, Dominguez G, Kossenkov AV, Donthireddy L, Veglia F, Lin C, Wang F, Fu S, Zhou J, Viatour P, Lavilla-Alonso S, Polo AT, Tcyganov EN, Mulligan C Jr, Nam B, Bennett J, Masters G, Guarino M, Kumar A, Nefedova Y, Vonderheide RH, Languino LR, Abrams SI, Gabrilovich DI. Mastio J, et al. Among authors: fu s. J Exp Med. 2019 Sep 2;216(9):2150-2169. doi: 10.1084/jem.20181952. Epub 2019 Jun 25. J Exp Med. 2019. PMID: 31239386 Free PMC article.
Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway.
Alicea-Torres K, Sanseviero E, Gui J, Chen J, Veglia F, Yu Q, Donthireddy L, Kossenkov A, Lin C, Fu S, Mulligan C, Nam B, Masters G, Denstman F, Bennett J, Hockstein N, Rynda-Apple A, Nefedova Y, Fuchs SY, Gabrilovich DI. Alicea-Torres K, et al. Among authors: fu s. Nat Commun. 2021 Mar 19;12(1):1717. doi: 10.1038/s41467-021-22033-2. Nat Commun. 2021. PMID: 33741967 Free PMC article.
A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression.
Deng H, Lin C, Garcia-Gerique L, Fu S, Cruz Z, Bonner EE, Rosenwasser M, Rajagopal S, Sadhu MN, Gajendran C, Zainuddin M, Gosu R, Sivanandhan D, Shelef MA, Nam B, Vogl DT, Gabrilovich DI, Nefedova Y. Deng H, et al. Among authors: fu s. Cancer Res. 2022 Oct 4;82(19):3561-3572. doi: 10.1158/0008-5472.CAN-21-4045. Cancer Res. 2022. PMID: 36069973 Free PMC article.
Syntaphilin Regulates Neutrophil Migration in Cancer.
Fu S, Deng H, Bertolini I, Perego M, Chen ES, Sanseviero E, Mostafa A, Alicea-Torres K, Garcia-Gerique L, Stone EL, Kossenkov AV, Schug ZT, Nam B, Mulligan C, Altieri DC, Nefedova Y, Gabrilovich DI. Fu S, et al. Cancer Immunol Res. 2023 Mar 1;11(3):278-289. doi: 10.1158/2326-6066.CIR-22-0035. Cancer Immunol Res. 2023. PMID: 36548516 Free PMC article.
Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells.
Peng M, Huang B, Zhang Q, Fu S, Wang D, Cheng X, Wu X, Xue Z, Zhang L, Zhang D, Da Y, Dai Y, Yang Q, Yao Z, Qiao L, Zhang R. Peng M, et al. Among authors: fu s. Cancer Lett. 2014 Nov 28;354(2):407-16. doi: 10.1016/j.canlet.2014.08.011. Epub 2014 Aug 13. Cancer Lett. 2014. PMID: 25128650
7,753 results