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Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells.
Pucci S, Bolchi C, Bavo F, Pallavicini M, De Palma C, Renzi M, Fucile S, Benfante R, Di Lascio S, Lattuada D, Bessereau JL, D'Alessandro M, Risson V, Zoli M, Clementi F, Gotti C. Pucci S, et al. Among authors: fucile s. Pharmacol Res. 2022 Jan;175:105959. doi: 10.1016/j.phrs.2021.105959. Epub 2021 Oct 28. Pharmacol Res. 2022. PMID: 34756924 Free article.
Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors.
Dallanoce C, Magrone P, Matera C, Frigerio F, Grazioso G, De Amici M, Fucile S, Piccari V, Frydenvang K, Pucci L, Gotti C, Clementi F, De Micheli C. Dallanoce C, et al. Among authors: fucile s. ChemMedChem. 2011 May 2;6(5):889-903. doi: 10.1002/cmdc.201000514. Epub 2011 Mar 1. ChemMedChem. 2011. PMID: 21365765
CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.
Sala M, Braida D, Pucci L, Manfredi I, Marks MJ, Wageman CR, Grady SR, Loi B, Fucile S, Fasoli F, Zoli M, Tasso B, Sparatore F, Clementi F, Gotti C. Sala M, et al. Among authors: fucile s. Br J Pharmacol. 2013 Feb;168(4):835-49. doi: 10.1111/j.1476-5381.2012.02204.x. Br J Pharmacol. 2013. PMID: 22957729 Free PMC article.
Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists.
Bolchi C, Valoti E, Gotti C, Fasoli F, Ruggeri P, Fumagalli L, Binda M, Mucchietto V, Sciaccaluga M, Budriesi R, Fucile S, Pallavicini M. Bolchi C, et al. Among authors: fucile s. J Med Chem. 2015 Aug 27;58(16):6665-77. doi: 10.1021/acs.jmedchem.5b00904. Epub 2015 Aug 18. J Med Chem. 2015. PMID: 26225816 Free article.
147 results