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Page 1
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
Molkentine JM, Fujimoto TN, Horvath TD, Grossberg AJ, Garcia CJG, Deorukhkar A, de la Cruz Bonilla M, Lin D, Samuel ELG, Chan WK, Lorenzi PL, Piwnica-Worms H, Dantzer R, Tour JM, Mason KA, Taniguchi CM. Molkentine JM, et al. Among authors: fujimoto tn. Sci Rep. 2019 Feb 13;9(1):1949. doi: 10.1038/s41598-018-37147-9. Sci Rep. 2019. PMID: 30760738 Free PMC article.
Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.
Fujimoto TN, Colbert LE, Huang Y, Molkentine JM, Deorukhkar A, Baseler L, de la Cruz Bonilla M, Yu M, Lin D, Gupta S, Cabeceiras PK, Kingsley CV, Tailor RC, Sawakuchi GO, Koay EJ, Piwnica-Worms H, Maitra A, Taniguchi CM. Fujimoto TN, et al. Cancer Res. 2019 May 1;79(9):2327-2338. doi: 10.1158/0008-5472.CAN-18-1785. Cancer Res. 2019. PMID: 31043430 Free PMC article.
Fasting Reduces Intestinal Radiotoxicity, Enabling Dose-Escalated Radiation Therapy for Pancreatic Cancer.
de la Cruz Bonilla M, Stemler KM, Jeter-Jones S, Fujimoto TN, Molkentine J, Asencio Torres GM, Zhang X, Broaddus RR, Taniguchi CM, Piwnica-Worms H. de la Cruz Bonilla M, et al. Among authors: fujimoto tn. Int J Radiat Oncol Biol Phys. 2019 Nov 1;105(3):537-547. doi: 10.1016/j.ijrobp.2019.06.2533. Epub 2019 Jul 2. Int J Radiat Oncol Biol Phys. 2019. PMID: 31271824 Free PMC article.
Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer.
Yu M, Nguyen ND, Huang Y, Lin D, Fujimoto TN, Molkentine JM, Deorukhkar A, Kang Y, San Lucas FA, Fernandes CJ, Koay EJ, Gupta S, Ying H, Koong AC, Herman JM, Fleming JB, Maitra A, Taniguchi CM. Yu M, et al. Among authors: fujimoto tn. JCI Insight. 2019 Jul 23;5(16):e126915. doi: 10.1172/jci.insight.126915. JCI Insight. 2019. PMID: 31335325 Free PMC article.
Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment.
Garcia Garcia CJ, Huang Y, Fuentes NR, Turner MC, Monberg ME, Lin D, Nguyen ND, Fujimoto TN, Zhao J, Lee JJ, Bernard V, Yu M, Delahoussaye AM, Jimenez Sacarello I, Caggiano EG, Phan JL, Deorukhkar A, Molkentine JM, Saur D, Maitra A, Taniguchi CM. Garcia Garcia CJ, et al. Among authors: fujimoto tn. Gastroenterology. 2022 Jun;162(7):2018-2031. doi: 10.1053/j.gastro.2022.02.024. Epub 2022 Feb 22. Gastroenterology. 2022. PMID: 35216965 Free PMC article.
Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2α in skeletal progenitor cells.
Guo W, Hoque J, Garcia Garcia CJ, Spiller KV, Leinroth AP, Puviindran V, Potnis CK, Gunn KA, Newman H, Ishikawa K, Fujimoto TN, Neill DW, Delahoussaye AM, Williams NT, Kirsch DG, Hilton MJ, Varghese S, Taniguchi CM, Wu C. Guo W, et al. Among authors: fujimoto tn. Sci Transl Med. 2023 Nov 29;15(724):eabo5217. doi: 10.1126/scitranslmed.abo5217. Epub 2023 Nov 29. Sci Transl Med. 2023. PMID: 38019933 Free PMC article.