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Accumulation of phosphorylated alpha-synuclein in aging human brain.
Saito Y, Kawashima A, Ruberu NN, Fujiwara H, Koyama S, Sawabe M, Arai T, Nagura H, Yamanouchi H, Hasegawa M, Iwatsubo T, Murayama S. Saito Y, et al. Among authors: fujiwara h. J Neuropathol Exp Neurol. 2003 Jun;62(6):644-54. doi: 10.1093/jnen/62.6.644. J Neuropathol Exp Neurol. 2003. PMID: 12834109
alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T. Fujiwara H, et al. Nat Cell Biol. 2002 Feb;4(2):160-4. doi: 10.1038/ncb748. Nat Cell Biol. 2002. PMID: 11813001
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions.
Hasegawa M, Fujiwara H, Nonaka T, Wakabayashi K, Takahashi H, Lee VM, Trojanowski JQ, Mann D, Iwatsubo T. Hasegawa M, et al. Among authors: fujiwara h. J Biol Chem. 2002 Dec 13;277(50):49071-6. doi: 10.1074/jbc.M208046200. Epub 2002 Oct 10. J Biol Chem. 2002. PMID: 12377775 Free article.
alpha-Synuclein is one of the major components of intracellular fibrillary aggregates in the brains of a subset of neurodegenerative disorders, including Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and Hallervorden-Spatz disease, which are referred to …
alpha-Synuclein is one of the major components of intracellular fibrillary aggregates in the brains of a subset of neurodegenerative disorde …
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies.
Neumann M, Kahle PJ, Giasson BI, Ozmen L, Borroni E, Spooren W, Müller V, Odoy S, Fujiwara H, Hasegawa M, Iwatsubo T, Trojanowski JQ, Kretzschmar HA, Haass C. Neumann M, et al. Among authors: fujiwara h. J Clin Invest. 2002 Nov;110(10):1429-39. doi: 10.1172/JCI15777. J Clin Invest. 2002. PMID: 12438441 Free PMC article.
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.
Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, Iwatsubo T, Trojanowski JQ. Lippa CF, et al. Among authors: fujiwara h. Am J Pathol. 1998 Nov;153(5):1365-70. doi: 10.1016/s0002-9440(10)65722-7. Am J Pathol. 1998. PMID: 9811326 Free PMC article.
3,605 results