Fulin Lian - Search Results

1

Sodium Oligomannate Electrostatically Binds to Aβ and Blocks Its Aggregation.

Zhou C, Zhang J, Luo X, Lian F, Zeng Y, Zhang Z, Zhang H, Zhang N. Zhou C, et al. Among authors: lian f. J Phys Chem B. 2023 Mar 9;127(9):1983-1994. doi: 10.1021/acs.jpcb.3c00280. Epub 2023 Feb 27. J Phys Chem B. 2023. PMID: 36848623

2

5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.

Wang S, Yang H, Su M, Lian F, Cong Z, Wei R, Zhou Y, Li X, Zheng X, Li C, Fu X, Han X, Shi Q, Li C, Zhang N, Geng M, Liu H, Li J, Huang X, Wang J. Wang S, et al. Among authors: lian f. Eur J Med Chem. 2021 Oct 15;222:113592. doi: 10.1016/j.ejmech.2021.113592. Epub 2021 Jun 5. Eur J Med Chem. 2021. PMID: 34147909

3

Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion.

Sun Z, Zhang H, Zhang Y, Liao L, Zhou W, Zhang F, Lian F, Huang J, Xu P, Zhang R, Lu W, Zhu M, Tao H, Yang F, Ding H, Chen S, Yue L, Zhou B, Zhang N, Tan M, Jiang H, Chen K, Liu B, Liu C, Dang Y, Luo C. Sun Z, et al. Among authors: lian f. Adv Sci (Weinh). 2020 May 13;7(14):2000098. doi: 10.1002/advs.202000098. eCollection 2020 Jul. Adv Sci (Weinh). 2020. PMID: 32714746 Free PMC article.

4

A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.

Wang Y, Huang J, Li B, Xue H, Tricot G, Hu L, Xu Z, Sun X, Chang S, Gao L, Tao Y, Xu H, Xie Y, Xiao W, Yu D, Kong Y, Chen G, Sun X, Lian F, Zhang N, Wu X, Mao Z, Zhan F, Zhu W, Shi J. Wang Y, et al. Among authors: lian f. Cancer Res. 2020 Feb 1;80(3):536-548. doi: 10.1158/0008-5472.CAN-18-3987. Epub 2019 Nov 15. Cancer Res. 2020. PMID: 31732653

5

Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors.

Lu W, Wang J, Li Y, Tao H, Xiong H, Lian F, Gao J, Ma H, Lu T, Zhang D, Ye X, Ding H, Yue L, Zhang Y, Tang H, Zhang N, Yang Y, Jiang H, Chen K, Zhou B, Luo C. Lu W, et al. Among authors: lian f. Eur J Med Chem. 2019 Dec 15;184:111767. doi: 10.1016/j.ejmech.2019.111767. Epub 2019 Oct 9. Eur J Med Chem. 2019. PMID: 31622854

6

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, Ni T, Zhang ZS, Zhang T, Li C, Han L, Zhu Z, Lian F, Wei J, Deng Q, Wang Y, Wunderlich M, Gao Z, Pan G, Zhong D, Zhou H, Zhang N, Gan J, Jiang H, Mulloy JC, Qian Z, Chen J, Yang CG. Huang Y, et al. Among authors: lian f. Cancer Cell. 2019 Apr 15;35(4):677-691.e10. doi: 10.1016/j.ccell.2019.03.006. Cancer Cell. 2019. PMID: 30991027 Free PMC article.

7

Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.

Zhang D, Han J, Lu W, Lian F, Wang J, Lu T, Tao H, Xiao S, Zhang F, Liu YC, Liu R, Zhang N, Jiang H, Chen K, Zhao C, Luo C. Zhang D, et al. Among authors: lian f. Bioorg Chem. 2019 May;86:494-500. doi: 10.1016/j.bioorg.2019.01.035. Epub 2019 Jan 28. Bioorg Chem. 2019. PMID: 30780018

8

The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening.

Ye X, Zhang R, Lian F, Zhang W, Lu W, Han J, Zhang N, Jin J, Luo C, Chen K, Ye F, Ding H. Ye X, et al. Among authors: lian f. Bioorg Med Chem Lett. 2019 Feb 15;29(4):638-645. doi: 10.1016/j.bmcl.2018.12.035. Epub 2018 Dec 17. Bioorg Med Chem Lett. 2019. PMID: 30626558

9

Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.

Chen D, Chen Y, Lian F, Chen L, Li Y, Cao D, Wang X, Chen L, Li J, Meng T, Huang M, Geng M, Shen J, Zhang N, Xiong B. Chen D, et al. Among authors: lian f. Eur J Med Chem. 2019 Feb 1;163:597-609. doi: 10.1016/j.ejmech.2018.12.018. Epub 2018 Dec 11. Eur J Med Chem. 2019. PMID: 30562696

10

Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells.

Wu D, Wang W, Chen W, Lian F, Lang L, Huang Y, Xu Y, Zhang N, Chen Y, Liu M, Nussinov R, Cheng F, Lu W, Huang J. Wu D, et al. Among authors: lian f. Haematologica. 2018 Sep;103(9):1472-1483. doi: 10.3324/haematol.2018.188185. Epub 2018 Jun 7. Haematologica. 2018. PMID: 29880605 Free PMC article.

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