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Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission.
J Pharmacol Sci. 2023 May;152(1):39-49. doi: 10.1016/j.jphs.2023.02.009. Epub 2023 Mar 14.
J Pharmacol Sci. 2023.
PMID: 37059490
Free article.
DIF-1 inhibits growth and metastasis of triple-negative breast cancer through AMPK-mediated inhibition of the mTORC1-S6K signaling pathway.
Seto-Tetsuo F, Arioka M, Miura K, Inoue T, Igawa K, Tomooka K, Takahashi-Yanaga F, Sasaguri T.
Seto-Tetsuo F, et al.
Oncogene. 2021 Sep;40(37):5579-5589. doi: 10.1038/s41388-021-01958-4. Epub 2021 Jul 24.
Oncogene. 2021.
PMID: 34304250
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Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells.
Arioka M, Seto-Tetsuo F, Inoue T, Miura K, Ishikane S, Igawa K, Tomooka K, Takahashi-Yanaga F, Sasaguri T.
Arioka M, et al. Among authors: seto tetsuo f.
Life Sci. 2023 Dec 15;335:122278. doi: 10.1016/j.lfs.2023.122278. Epub 2023 Nov 18.
Life Sci. 2023.
PMID: 37981227
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DIF-1 exhibits anticancer activity in breast cancer via inhibition of CXCLs/CXCR2 axis-mediated communication between cancer-associated fibroblasts and cancer cells.
Seto-Tetsuo F, Arioka M, Miura K, Inoue T, Igawa K, Tomooka K, Sasaguri T.
Seto-Tetsuo F, et al.
Int Immunopharmacol. 2023 Apr;117:109913. doi: 10.1016/j.intimp.2023.109913. Epub 2023 Feb 20.
Int Immunopharmacol. 2023.
PMID: 36812674
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