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Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer.
Jee J, Lebow ES, Yeh R, Das JP, Namakydoust A, Paik PK, Chaft JE, Jayakumaran G, Rose Brannon A, Benayed R, Zehir A, Donoghue M, Schultz N, Chakravarty D, Kundra R, Madupuri R, Murciano-Goroff YR, Tu HY, Xu CR, Martinez A, Wilhelm C, Galle J, Daly B, Yu HA, Offin M, Hellmann MD, Lito P, Arbour KC, Zauderer MG, Kris MG, Ng KK, Eng J, Preeshagul I, Victoria Lai W, Fiore JJ, Iqbal A, Molena D, Rocco G, Park BJ, Lim LP, Li M, Tong-Li C, De Silva M, Chan DL, Diakos CI, Itchins M, Clarke S, Pavlakis N, Lee A, Rekhtman N, Chang J, Travis WD, Riely GJ, Solit DB, Gonen M, Rusch VW, Rimner A, Gomez D, Drilon A, Scher HI, Shah SP, Berger MF, Arcila ME, Ladanyi M, Levine RL, Shen R, Razavi P, Reis-Filho JS, Jones DR, Rudin CM, Isbell JM, Li BT. Jee J, et al. Among authors: jayakumaran g. Nat Med. 2022 Nov;28(11):2353-2363. doi: 10.1038/s41591-022-02047-z. Epub 2022 Nov 10. Nat Med. 2022. PMID: 36357680 Free PMC article.
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.
Rose Brannon A, Jayakumaran G, Diosdado M, Patel J, Razumova A, Hu Y, Meng F, Haque M, Sadowska J, Murphy BJ, Baldi T, Johnson I, Ptashkin R, Hasan M, Srinivasan P, Rema AB, Rijo I, Agarunov A, Won H, Perera D, Brown DN, Samoila A, Jing X, Gedvilaite E, Yang JL, Stephens DP, Dix JM, DeGroat N, Nafa K, Syed A, Li A, Lebow ES, Bowman AS, Ferguson DC, Liu Y, Mata DA, Sharma R, Yang SR, Bale T, Benhamida JK, Chang JC, Dogan S, Hameed MR, Hechtman JF, Moung C, Ross DS, Vakiani E, Vanderbilt CM, Yao J, Razavi P, Smyth LM, Chandarlapaty S, Iyer G, Abida W, Harding JJ, Krantz B, O'Reilly E, Yu HA, Li BT, Rudin CM, Diaz L, Solit DB, Arcila ME, Ladanyi M, Loomis B, Tsui D, Berger MF, Zehir A, Benayed R. Rose Brannon A, et al. Among authors: jayakumaran g. Nat Commun. 2021 Jun 18;12(1):3770. doi: 10.1038/s41467-021-24109-5. Nat Commun. 2021. PMID: 34145282 Free PMC article.
Enhanced Aerosol Delivery During High-Flow Nasal Cannula Therapy.
Moon J, McPeck M, Jayakumaran J, Smaldone GC. Moon J, et al. Among authors: jayakumaran j. Respir Care. 2023 Sep;68(9):1221-1228. doi: 10.4187/respcare.10644. Epub 2023 May 30. Respir Care. 2023. PMID: 37253612
Aerosol delivery to the trachea was measured by using a shielded ratemeter, which defined the rate of drug delivery (g NaCl/min). RESULTS: With increasing gas flow, breath-enhanced jet nebulizer output increased to a maximum of 50 mL/h, the vibrating mesh nebulizer maximum …
Aerosol delivery to the trachea was measured by using a shielded ratemeter, which defined the rate of drug delivery (g NaCl/min). RES …
Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study.
Abramson DH, Mandelker DL, Brannon AR, Dunkel IJ, Benayed R, Berger MF, Arcila ME, Ladanyi M, Friedman DN, Jayakumaran G, Diosdado MS, Robbins MA, Haggag-Lindgren D, Shukla N, Walsh MF, Kothari P, Tsui DWY, Francis JH. Abramson DH, et al. Among authors: jayakumaran g. PLoS One. 2023 Feb 3;18(2):e0271505. doi: 10.1371/journal.pone.0271505. eCollection 2023. PLoS One. 2023. PMID: 36735656 Free PMC article.
Novel Germline Mutations in DNA Damage Repair in Patients with Malignant Pleural Mesotheliomas.
Guo R, DuBoff M, Jayakumaran G, Kris MG, Ladanyi M, Robson ME, Mandelker D, Zauderer MG. Guo R, et al. Among authors: jayakumaran g. J Thorac Oncol. 2020 Apr;15(4):655-660. doi: 10.1016/j.jtho.2019.12.111. Epub 2019 Dec 28. J Thorac Oncol. 2020. PMID: 31887429 Free PMC article.
INTRODUCTION: Although next-generation sequencing (NGS) has brought insight into critical mutations or pathways (e.g., DNA damage sensing and repair) involved in the etiology of many cancers and has directed new screening, prevention, and therapeutic approaches for patient …
INTRODUCTION: Although next-generation sequencing (NGS) has brought insight into critical mutations or pathways (e.g., DNA damage sen …
In Vivo Deposition of High-Flow Nasal Aerosols Using Breath-Enhanced Nebulization.
Jayakumaran J, Smaldone GC. Jayakumaran J, et al. Pharmaceutics. 2024 Jan 28;16(2):182. doi: 10.3390/pharmaceutics16020182. Pharmaceutics. 2024. PMID: 38399243 Free PMC article.
Rates of aerosol deposition in the lungs (Ci/min) were measured via a gamma camera for each infusion rate and converted to g NaCl/min. The deposition rate, as expressed as g of NaCl/min, was closely related to the infusion rate: 7.84 3.2 at 12 mL/h, 43.0 12 at 20 mL …
Rates of aerosol deposition in the lungs (Ci/min) were measured via a gamma camera for each infusion rate and converted to g NaCl/min …