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Page 1
Mechanisms of immunosenescence.
Caruso C, Buffa S, Candore G, Colonna-Romano G, Dunn-Walters D, Kipling D, Pawelec G. Caruso C, et al. Among authors: pawelec g. Immun Ageing. 2009 Jul 22;6:10. doi: 10.1186/1742-4933-6-10. Immun Ageing. 2009. PMID: 19624841 Free PMC article.
On April 7,8, 2009 a Symposium entitled "Pathophysiology of Successful and Unsuccessful Ageing" took place in Palermo, Italy. Here, the lectures of G. Pawelec, D. Dunn-Walters and. G. Colonna-Romano on T and B immunosenescence are summarized. ...
On April 7,8, 2009 a Symposium entitled "Pathophysiology of Successful and Unsuccessful Ageing" took place in Palermo, Italy. Here, the lect …
Aberrant Complement System Activation in Neurological Disorders.
Ziabska K, Ziemka-Nalecz M, Pawelec P, Sypecka J, Zalewska T. Ziabska K, et al. Among authors: pawelec p. Int J Mol Sci. 2021 Apr 28;22(9):4675. doi: 10.3390/ijms22094675. Int J Mol Sci. 2021. PMID: 33925147 Free PMC article. Review.
During the last decade, there has been a growing interest in the role that this cascading pathway plays in the neuropathology of a diverse array of brain disorders (e.g., acute neurotraumatic insult, chronic neurodegenerative diseases, and psychiatric disturbances) in whic …
During the last decade, there has been a growing interest in the role that this cascading pathway plays in the neuropathology of a diverse a …
Immunorejuvenation in the elderly.
Pawelec G, Koch S, Gouttefangeas C, Wikby A. Pawelec G, et al. Rejuvenation Res. 2006 Spring;9(1):111-6. doi: 10.1089/rej.2006.9.111. Rejuvenation Res. 2006. PMID: 16608407 Review.
This, coupled with methods directed at reinvigorating the thymus (e.g., use of interleukin 7), and targeting CMV by pharmacologic and immunotherapeutic interventions might result in a degree of "immunorejuvenation" sufficient to take elderly individuals out of the risk cat …
This, coupled with methods directed at reinvigorating the thymus (e.g., use of interleukin 7), and targeting CMV by pharmacologic and …
First trimester pregnancy loss: Clinical implications of genetic testing.
Massalska D, Zimowski JG, Bijok J, Pawelec M, Czubak-Barlik M, Jakiel G, Roszkowski T. Massalska D, et al. Among authors: pawelec m. J Obstet Gynaecol Res. 2017 Jan;43(1):23-29. doi: 10.1111/jog.13179. Epub 2016 Dec 8. J Obstet Gynaecol Res. 2017. PMID: 27928862 Review.
Around 10-15% of pregnancies result in a spontaneous first trimester miscarriage, which is most frequently caused by chromosomal abnormalities, mainly aneuploidies. Genetic analysis of pregnancy loss includes conventional G-banding karyotyping and various molecular methods …
Around 10-15% of pregnancies result in a spontaneous first trimester miscarriage, which is most frequently caused by chromosomal abnormaliti …
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Moha… See abstract for full author list ➔ Block KI, et al. Among authors: pawelec g. Semin Cancer Biol. 2015 Dec;35 Suppl(Suppl):S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Semin Cancer Biol. 2015. PMID: 26590477 Free PMC article. Review.
Immune receptor signaling, aging and autoimmunity.
Larbi A, Fülöp T, Pawelec G. Larbi A, et al. Among authors: pawelec g. Adv Exp Med Biol. 2008;640:312-24. doi: 10.1007/978-0-387-09789-3_21. Adv Exp Med Biol. 2008. PMID: 19065799 Review.
Certain similar changes have also been found in some other disease states, e.g., rheumatoid arthritis, systemic lupus erythematosus and cancer. ...
Certain similar changes have also been found in some other disease states, e.g., rheumatoid arthritis, systemic lupus erythematosus a …
Neuroimmunology and ageing - the state of the art.
Bauer ME, Pawelec G, Paganelli R. Bauer ME, et al. Among authors: pawelec g. Immun Ageing. 2024 Jan 10;21(1):5. doi: 10.1186/s12979-024-00411-w. Immun Ageing. 2024. PMID: 38200570 Free PMC article. No abstract available.
Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
Pallis AG, Hatse S, Brouwers B, Pawelec G, Falandry C, Wedding U, Lago LD, Repetto L, Ring A, Wildiers H. Pallis AG, et al. Among authors: pawelec g. J Geriatr Oncol. 2014 Apr;5(2):204-18. doi: 10.1016/j.jgo.2013.09.001. Epub 2013 Sep 29. J Geriatr Oncol. 2014. PMID: 24495695 Review.
On the other hand, aging can also be assessed in terms of biological changes in certain tissues like the blood compartment which result from adaptive alterations due to past history of exposures, as well as intrinsic aging processes. There are major signs of 'aging' in lymphocyte …
On the other hand, aging can also be assessed in terms of biological changes in certain tissues like the blood compartment which result from …
New methods to approach immunotherapy of cancer--and strategies of tumours to avoid elimination. Conference report, on behalf of EUCAPS. European Cancer Research Consortium.
Pawelec G. Pawelec G. Cancer Immunol Immunother. 2000 Jul;49(4-5):276-80. doi: 10.1007/s002620000119. Cancer Immunol Immunother. 2000. PMID: 10941911
This conference was the second of a series, the first of which was summarised previously in this journal [Pawelec G et al. (1999) Cancer Immunol Immunother 48: 214]....
This conference was the second of a series, the first of which was summarised previously in this journal [Pawelec G et al. (1999) Can …
62 results