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Page 1
Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
Cancer Res. 2021 Apr 15;81(8):2128-2141. doi: 10.1158/0008-5472.CAN-20-2860. Epub 2021 Jan 28.
Cancer Res. 2021.
PMID: 33509941
Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.
Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, Verrill C, Bryant RJ, Han C, Hutchinson K, Lambert AG, Kumar R, Hamdy FC, Weyer-Czernilofsky U, Sanderson MP, Bogenrieder T, Taylor S, Macaulay VM.
Aleksic T, et al.
Cancer Res. 2018 Jul 1;78(13):3497-3509. doi: 10.1158/0008-5472.CAN-17-3498. Epub 2018 May 7.
Cancer Res. 2018.
PMID: 29735545
Free PMC article.
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IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.
Aleksic T, Verrill C, Bryant RJ, Han C, Worrall AR, Brureau L, Larré S, Higgins GS, Fazal F, Sabbagh A, Haider S, Buffa FM, Cole D, Macaulay VM.
Aleksic T, et al.
Br J Cancer. 2017 Nov 21;117(11):1600-1606. doi: 10.1038/bjc.2017.337. Epub 2017 Oct 3.
Br J Cancer. 2017.
PMID: 28972962
Free PMC article.
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Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition.
Lodhia KA, Gao S, Aleksic T, Esashi F, Macaulay VM.
Lodhia KA, et al.
Int J Cancer. 2015 Jun 15;136(12):2961-6. doi: 10.1002/ijc.29327. Epub 2014 Nov 25.
Int J Cancer. 2015.
PMID: 25388513
Free PMC article.
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IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.
Chitnis MM, Lodhia KA, Aleksic T, Gao S, Protheroe AS, Macaulay VM.
Chitnis MM, et al.
Oncogene. 2014 Nov 6;33(45):5262-73. doi: 10.1038/onc.2013.460. Epub 2013 Nov 4.
Oncogene. 2014.
PMID: 24186206
Free PMC article.
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