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The dually acylated NH2-terminal domain of gi1alpha is sufficient to target a green fluorescent protein reporter to caveolin-enriched plasma membrane domains. Palmitoylation of caveolin-1 is required for the recognition of dually acylated g-protein alpha subunits in vivo.
Galbiati F, Volonte D, Meani D, Milligan G, Lublin DM, Lisanti MP, Parenti M. Galbiati F, et al. J Biol Chem. 1999 Feb 26;274(9):5843-50. doi: 10.1074/jbc.274.9.5843. J Biol Chem. 1999. PMID: 10026207 Free article.
Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myotube formation.
Galbiati F, Volonte D, Engelman JA, Scherer PE, Lisanti MP. Galbiati F, et al. J Biol Chem. 1999 Oct 15;274(42):30315-21. doi: 10.1074/jbc.274.42.30315. J Biol Chem. 1999. PMID: 10514527 Free article.
152 results