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Mitochondria metabolism sets the species-specific tempo of neuronal development.
Iwata R, Casimir P, Erkol E, Boubakar L, Planque M, Gallego López IM, Ditkowska M, Gaspariunaite V, Beckers S, Remans D, Vints K, Vandekeere A, Poovathingal S, Bird M, Vlaeminck I, Creemers E, Wierda K, Corthout N, Vermeersch P, Carpentier S, Davie K, Mazzone M, Gounko NV, Aerts S, Ghesquière B, Fendt SM, Vanderhaeghen P. Iwata R, et al. Among authors: gallego lopez im. Science. 2023 Feb 10;379(6632):eabn4705. doi: 10.1126/science.abn4705. Epub 2023 Feb 10. Science. 2023. PMID: 36705539
FASN-dependent de novo lipogenesis is required for brain development.
Gonzalez-Bohorquez D, Gallego López IM, Jaeger BN, Pfammatter S, Bowers M, Semenkovich CF, Jessberger S. Gonzalez-Bohorquez D, et al. Among authors: gallego lopez im. Proc Natl Acad Sci U S A. 2022 Jan 11;119(2):e2112040119. doi: 10.1073/pnas.2112040119. Proc Natl Acad Sci U S A. 2022. PMID: 34996870 Free PMC article.