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Page 1
Brd4 is required for chondrocyte differentiation and endochondral ossification.
Paradise CR, Galvan ML, Pichurin O, Jerez S, Kubrova E, Dehghani SS, Carrasco ME, Thaler R, Larson AN, van Wijnen AJ, Dudakovic A. Paradise CR, et al. Among authors: galvan ml. Bone. 2022 Jan;154:116234. doi: 10.1016/j.bone.2021.116234. Epub 2021 Oct 23. Bone. 2022. PMID: 34700039 Free PMC article.
The epigenetic reader Brd4 is required for osteoblast differentiation.
Paradise CR, Galvan ML, Kubrova E, Bowden S, Liu E, Carstens MF, Thaler R, Stein GS, van Wijnen AJ, Dudakovic A. Paradise CR, et al. Among authors: galvan ml. J Cell Physiol. 2020 Jun;235(6):5293-5304. doi: 10.1002/jcp.29415. Epub 2019 Dec 23. J Cell Physiol. 2020. PMID: 31868237 Free PMC article.
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2.
Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, Westendorf JJ, Cool SM, van Wijnen AJ. Dudakovic A, et al. Among authors: galvan ml. J Biol Chem. 2020 Jun 5;295(23):7877-7893. doi: 10.1074/jbc.RA119.011685. Epub 2020 Apr 24. J Biol Chem. 2020. PMID: 32332097 Free PMC article.