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Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.
Girotti MR, Gremel G, Lee R, Galvani E, Rothwell D, Viros A, Mandal AK, Lim KH, Saturno G, Furney SJ, Baenke F, Pedersen M, Rogan J, Swan J, Smith M, Fusi A, Oudit D, Dhomen N, Brady G, Lorigan P, Dive C, Marais R. Girotti MR, et al. Among authors: galvani e. Cancer Discov. 2016 Mar;6(3):286-99. doi: 10.1158/2159-8290.CD-15-1336. Epub 2015 Dec 29. Cancer Discov. 2016. PMID: 26715644
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Galvani E, Mundra PA, Valpione S, Garcia-Martinez P, Smith M, Greenall J, Thakur R, Helmink B, Andrews MC, Boon L, Chester C, Gremel G, Hogan K, Mandal A, Zeng K, Banyard A, Ashton G, Cook M, Lorigan P, Wargo JA, Dhomen N, Marais R. Galvani E, et al. Nat Commun. 2020 Feb 12;11(1):853. doi: 10.1038/s41467-020-14632-2. Nat Commun. 2020. PMID: 32051401 Free PMC article.
Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy.
Valpione S, Galvani E, Tweedy J, Mundra PA, Banyard A, Middlehurst P, Barry J, Mills S, Salih Z, Weightman J, Gupta A, Gremel G, Baenke F, Dhomen N, Lorigan PC, Marais R. Valpione S, et al. Among authors: galvani e. Nat Cancer. 2020 Feb;1(2):210-221. doi: 10.1038/s43018-019-0022-x. Epub 2020 Feb 10. Nat Cancer. 2020. PMID: 32110781 Free PMC article.
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
Lee RJ, Khandelwal G, Baenke F, Cannistraci A, Macleod K, Mundra P, Ashton G, Mandal A, Viros A, Gremel G, Galvani E, Smith M, Carragher N, Dhomen N, Miller C, Lorigan P, Marais R. Lee RJ, et al. Among authors: galvani e. ESMO Open. 2020 Aug;5(4):e000707. doi: 10.1136/esmoopen-2020-000707. ESMO Open. 2020. PMID: 32817058 Free PMC article.
T cell immune awakening in response to immunotherapy is age-dependent.
Salih Z, Banyard A, Tweedy J, Galvani E, Middlehurst P, Mills S, Weightman J, Gupta A, Lorigan PC, Zhou C, Dhomen N, Valpione S, Marais R. Salih Z, et al. Among authors: galvani e. Eur J Cancer. 2022 Feb;162:11-21. doi: 10.1016/j.ejca.2021.11.015. Epub 2021 Dec 21. Eur J Cancer. 2022. PMID: 34952479 Free PMC article.
Tumour infiltrating B cells discriminate checkpoint blockade-induced responses.
Valpione S, Campana LG, Weightman J, Salih Z, Galvani E, Mundra PA, De Rosa F, Gupta A, Serra-Bellver P, Lorigan P, Germetaki T, Dynowski M, Kitcatt S, Sahoo S, Lee D, Dhomen N, Lord G, Marais R. Valpione S, et al. Among authors: galvani e. Eur J Cancer. 2022 Dec;177:164-174. doi: 10.1016/j.ejca.2022.09.022. Epub 2022 Oct 5. Eur J Cancer. 2022. PMID: 36347135 Free article.
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines.
Cavazzoni A, Alfieri RR, Cretella D, Saccani F, Ampollini L, Galetti M, Quaini F, Graiani G, Madeddu D, Mozzoni P, Galvani E, La Monica S, Bonelli M, Fumarola C, Mutti A, Carbognani P, Tiseo M, Barocelli E, Petronini PG, Ardizzoni A. Cavazzoni A, et al. Among authors: galvani e. Mol Cancer. 2012 Dec 12;11:91. doi: 10.1186/1476-4598-11-91. Mol Cancer. 2012. PMID: 23234355 Free PMC article.
56 results