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AMP-activated protein kinase: nature's energy sensor.
Carling D, Mayer FV, Sanders MJ, Gamblin SJ. Carling D, et al. Among authors: gamblin sj. Nat Chem Biol. 2011 Jul 18;7(8):512-8. doi: 10.1038/nchembio.610. Nat Chem Biol. 2011. PMID: 21769098 Review.
Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Xiao B, Heath R, Saiu P, Leiper FC, Leone P, Jing C, Walker PA, Haire L, Eccleston JF, Davis CT, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nature. 2007 Sep 27;449(7161):496-500. doi: 10.1038/nature06161. Epub 2007 Sep 12. Nature. 2007. PMID: 17851531
Structure of mammalian AMPK and its regulation by ADP.
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13. Nature. 2011. PMID: 21399626 Free PMC article.
AMP-activated protein kinase: also regulated by ADP?
Hardie DG, Carling D, Gamblin SJ. Hardie DG, et al. Among authors: gamblin sj. Trends Biochem Sci. 2011 Sep;36(9):470-7. doi: 10.1016/j.tibs.2011.06.004. Epub 2011 Jul 23. Trends Biochem Sci. 2011. PMID: 21782450 Review.
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase.
Mayer FV, Heath R, Underwood E, Sanders MJ, Carmena D, McCartney RR, Leiper FC, Xiao B, Jing C, Walker PA, Haire LF, Ogrodowicz R, Martin SR, Schmidt MC, Gamblin SJ, Carling D. Mayer FV, et al. Among authors: gamblin sj. Cell Metab. 2011 Nov 2;14(5):707-14. doi: 10.1016/j.cmet.2011.09.009. Epub 2011 Oct 20. Cell Metab. 2011. PMID: 22019086 Free PMC article.
Structural basis of AMPK regulation by small molecule activators.
Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017. Nat Commun. 2013. PMID: 24352254 Free PMC article.
The structure of the GTPase-activating domain from p50rhoGAP.
Barrett T, Xiao B, Dodson EJ, Dodson G, Ludbrook SB, Nurmahomed K, Gamblin SJ, Musacchio A, Smerdon SJ, Eccleston JF. Barrett T, et al. Among authors: gamblin sj. Nature. 1997 Jan 30;385(6615):458-61. doi: 10.1038/385458a0. Nature. 1997. PMID: 9009196
108 results