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GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: gao t. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.
Nelson BS, Lin L, Kremer DM, Sousa CM, Cotta-Ramusino C, Myers A, Ramos J, Gao T, Kovalenko I, Wilder-Romans K, Dresser J, Davis M, Lee HJ, Nwosu ZC, Campit S, Mashadova O, Nicolay BN, Tolstyka ZP, Halbrook CJ, Chandrasekaran S, Asara JM, Crawford HC, Cantley LC, Kimmelman AC, Wahl DR, Lyssiotis CA. Nelson BS, et al. Among authors: gao t. Cancer Metab. 2020 Jan 2;8:1. doi: 10.1186/s40170-019-0202-2. eCollection 2020. Cancer Metab. 2020. PMID: 31908776 Free PMC article.
KLF15-Cyp3a11 Axis Regulates Rifampicin-induced Liver Injury.
Hou W, Huo KG, Guo X, Xu M, Yang Y, Shi Z, Xu W, Tu J, Gao T, Ma Z, Han S. Hou W, et al. Among authors: gao t. Drug Metab Dispos. 2024 Apr 26:DMD-AR-2023-001617. doi: 10.1124/dmd.123.001617. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38670799
The safety and tolerability of a one strength dose-escalation scheme for subcutaneous immunotherapy with a native house dust mite extract in Chinese children: A multicenter, randomized, open label clinical trial.
Zhi L, Bai Y, Liao W, Chen G, Gao T, Wan X, Liang J, Liu L, Chen L, Zhang W, Bai J. Zhi L, et al. Among authors: gao t. Heliyon. 2024 Apr 10;10(8):e29450. doi: 10.1016/j.heliyon.2024.e29450. eCollection 2024 Apr 30. Heliyon. 2024. PMID: 38655350 Free PMC article.
4,221 results