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Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering.
Tan DS, Chen Y, Gao Y, Bednarz A, Wei Y, Malik V, Ho DH, Weng M, Ho SY, Srivastava Y, Velychko S, Yang X, Fan L, Kim J, Graumann J, Stormo GD, Braun T, Yan J, Schöler HR, Jauch R. Tan DS, et al. Among authors: gao y. Mol Biol Evol. 2021 Jun 25;38(7):2854-2868. doi: 10.1093/molbev/msab075. Mol Biol Evol. 2021. PMID: 33720298 Free PMC article.
The homeodomain of Oct4 is a dimeric binder of methylated CpG elements.
Tan DS, Cheung SL, Gao Y, Weinbuch M, Hu H, Shi L, Ti SC, Hutchins AP, Cojocaru V, Jauch R. Tan DS, et al. Among authors: gao y. Nucleic Acids Res. 2023 Feb 22;51(3):1120-1138. doi: 10.1093/nar/gkac1262. Nucleic Acids Res. 2023. PMID: 36631980 Free PMC article.
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