García-Sastre A - Search Results

1

Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.

Shi M, Cho H, Inn KS, Yang A, Zhao Z, Liang Q, Versteeg GA, Amini-Bavil-Olyaee S, Wong LY, Zlokovic BV, Park HS, García-Sastre A, Jung JU. Shi M, et al. Nat Commun. 2014 Sep 5;5:4820. doi: 10.1038/ncomms5820. Nat Commun. 2014. PMID: 25190485 Free PMC article.

2

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.

Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A. Gack MU, et al. Cell Host Microbe. 2009 May 8;5(5):439-49. doi: 10.1016/j.chom.2009.04.006. Cell Host Microbe. 2009. PMID: 19454348 Free PMC article.

3

Phosphorylation-mediated negative regulation of RIG-I antiviral activity.

Gack MU, Nistal-Villán E, Inn KS, García-Sastre A, Jung JU. Gack MU, et al. J Virol. 2010 Apr;84(7):3220-9. doi: 10.1128/JVI.02241-09. Epub 2010 Jan 13. J Virol. 2010. PMID: 20071582 Free PMC article.

4

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein.

Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, García-Sastre A. Versteeg GA, et al. J Virol. 2010 May;84(10):5423-30. doi: 10.1128/JVI.02395-09. Epub 2010 Mar 10. J Virol. 2010. PMID: 20219937 Free PMC article.

5

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.

Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A. Nistal-Villán E, et al. J Biol Chem. 2010 Jun 25;285(26):20252-61. doi: 10.1074/jbc.M109.089912. Epub 2010 Apr 20. J Biol Chem. 2010. PMID: 20406818 Free PMC article.

6

Viral tricks to grid-lock the type I interferon system.

Versteeg GA, García-Sastre A. Versteeg GA, et al. Curr Opin Microbiol. 2010 Aug;13(4):508-16. doi: 10.1016/j.mib.2010.05.009. Epub 2010 Jun 10. Curr Opin Microbiol. 2010. PMID: 20538505 Free PMC article. Review.

7

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.

Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.

8

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.

Oudshoorn D, van Boheemen S, Sánchez-Aparicio MT, Rajsbaum R, García-Sastre A, Versteeg GA. Oudshoorn D, et al. PLoS One. 2012;7(1):e29870. doi: 10.1371/journal.pone.0029870. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272257 Free PMC article.

9

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU. Rajsbaum R, et al. PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29. PLoS Pathog. 2012. PMID: 23209422 Free PMC article.

10

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.

Versteeg GA, Rajsbaum R, Sánchez-Aparicio MT, Maestre AM, Valdiviezo J, Shi M, Inn KS, Fernandez-Sesma A, Jung J, García-Sastre A. Versteeg GA, et al. Immunity. 2013 Feb 21;38(2):384-98. doi: 10.1016/j.immuni.2012.11.013. Immunity. 2013. PMID: 23438823 Free PMC article.

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