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The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers.
Parato KA, Breitbach CJ, Le Boeuf F, Wang J, Storbeck C, Ilkow C, Diallo JS, Falls T, Burns J, Garcia V, Kanji F, Evgin L, Hu K, Paradis F, Knowles S, Hwang TH, Vanderhyden BC, Auer R, Kirn DH, Bell JC. Parato KA, et al. Among authors: garcia v. Mol Ther. 2012 Apr;20(4):749-58. doi: 10.1038/mt.2011.276. Epub 2011 Dec 20. Mol Ther. 2012. PMID: 22186794 Free PMC article.
Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine.
Lemay CG, Rintoul JL, Kus A, Paterson JM, Garcia V, Falls TJ, Ferreira L, Bridle BW, Conrad DP, Tang VA, Diallo JS, Arulanandam R, Le Boeuf F, Garson K, Vanderhyden BC, Stojdl DF, Lichty BD, Atkins HL, Parato KA, Bell JC, Auer RC. Lemay CG, et al. Among authors: garcia v. Mol Ther. 2012 Sep;20(9):1791-9. doi: 10.1038/mt.2012.128. Epub 2012 Jul 3. Mol Ther. 2012. PMID: 22760544 Free PMC article.
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.
Arulanandam R, Batenchuk C, Varette O, Zakaria C, Garcia V, Forbes NE, Davis C, Krishnan R, Karmacharya R, Cox J, Sinha A, Babawy A, Waite K, Weinstein E, Falls T, Chen A, Hamill J, De Silva N, Conrad DP, Atkins H, Garson K, Ilkow C, Kærn M, Vanderhyden B, Sonenberg N, Alain T, Le Boeuf F, Bell JC, Diallo JS. Arulanandam R, et al. Among authors: garcia v. Nat Commun. 2015 Mar 30;6:6410. doi: 10.1038/ncomms7410. Nat Commun. 2015. PMID: 25817275 Free article.
Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity.
Bourgeois-Daigneault MC, Roy DG, Falls T, Twumasi-Boateng K, St-Germain LE, Marguerie M, Garcia V, Selman M, Jennings VA, Pettigrew J, Amos S, Diallo JS, Nelson B, Bell JC. Bourgeois-Daigneault MC, et al. Among authors: garcia v. Mol Ther Oncolytics. 2016 Feb 17;3:16001. doi: 10.1038/mto.2016.1. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 27119116 Free PMC article.
The strategic combination of trastuzumab emtansine with oncolytic rhabdoviruses leads to therapeutic synergy.
Arulanandam R, Taha Z, Garcia V, Selman M, Chen A, Varette O, Jirovec A, Sutherland K, Macdonald E, Tzelepis F, Birdi H, Alluqmani N, Landry A, Bergeron A, Vanderhyden B, Diallo JS. Arulanandam R, et al. Among authors: garcia v. Commun Biol. 2020 May 22;3(1):254. doi: 10.1038/s42003-020-0972-7. Commun Biol. 2020. PMID: 32444806 Free PMC article.
Perspective on Lignin Conversion Strategies That Enable Next Generation Biorefineries.
Shrestha S, Goswami S, Banerjee D, Garcia V, Zhou E, Olmsted CN, Majumder EL, Kumar D, Awasthi D, Mukhopadhyay A, Singer SW, Gladden JM, Simmons BA, Choudhary H. Shrestha S, et al. Among authors: garcia v. ChemSusChem. 2024 Apr 26:e202301460. doi: 10.1002/cssc.202301460. Online ahead of print. ChemSusChem. 2024. PMID: 38669480 Review.
1,640 results