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Year Number of Results
2014 1
2015 1
2017 2
2018 1
2019 3
2020 7
2021 3
2022 1
2023 1
2024 1

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20 results

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Page 1
Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation.
Núñez FJ, Banerjee K, Mujeeb AA, Mauser A, Tronrud CE, Zhu Z, Taher A, Kadiyala P, Carney SV, Garcia-Fabiani MB, Comba A, Alghamri MS, McClellan BL, Faisal SM, Nwosu ZC, Hong HS, Qin T, Sartor MA, Ljungman M, Cheng SY, Appelman HD, Lowenstein PR, Lahann J, Lyssiotis CA, Castro MG. Núñez FJ, et al. Among authors: garcia fabiani mb. bioRxiv [Preprint]. 2024 Mar 13:2024.03.08.584091. doi: 10.1101/2024.03.08.584091. bioRxiv. 2024. PMID: 38559270 Free PMC article. Preprint.
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas.
Garcia-Fabiani MB, Haase S, Banerjee K, McClellan B, Zhu Z, Mujeeb A, Li Y, Yu J, Kadiyala P, Taher A, Núñez FJ, Alghamri MS, Comba A, Mendez FM, Nicola Candia AJ, Salazar B, Koschmann C, Nunez FM, Edwards M, Qin T, Sartor MA, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. bioRxiv [Preprint]. 2023 Jun 13:2023.06.13.544658. doi: 10.1101/2023.06.13.544658. bioRxiv. 2023. PMID: 37398299 Free PMC article. Preprint.
H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Haase S, Banerjee K, Mujeeb AA, Hartlage CS, Núñez FM, Núñez FJ, Alghamri MS, Kadiyala P, Carney S, Barissi MN, Taher AW, Brumley EK, Thompson S, Dreyer JT, Alindogan CT, Garcia-Fabiani MB, Comba A, Venneti S, Ravikumar V, Koschmann C, Carcaboso ÁM, Vinci M, Rao A, Yu JS, Lowenstein PR, Castro MG. Haase S, et al. Among authors: garcia fabiani mb. J Clin Invest. 2022 Nov 15;132(22):e154229. doi: 10.1172/JCI154229. J Clin Invest. 2022. PMID: 36125896 Free PMC article.
G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy.
Alghamri MS, McClellan BL, Avvari RP, Thalla R, Carney S, Hartlage CS, Haase S, Ventosa M, Taher A, Kamran N, Zhang L, Faisal SM, Núñez FJ, Garcia-Fabiani MB, Al-Holou WN, Orringer D, Hervey-Jumper S, Heth J, Patil PG, Eddy K, Merajver SD, Ulintz PJ, Welch J, Gao C, Liu J, Núñez G, Hambardzumyan D, Lowenstein PR, Castro MG. Alghamri MS, et al. Among authors: garcia fabiani mb. Sci Adv. 2021 Oct;7(40):eabh3243. doi: 10.1126/sciadv.abh3243. Epub 2021 Sep 29. Sci Adv. 2021. PMID: 34586841 Free PMC article.
Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies.
Garcia-Fabiani MB, Haase S, Comba A, Carney S, McClellan B, Banerjee K, Alghamri MS, Syed F, Kadiyala P, Nunez FJ, Candolfi M, Asad A, Gonzalez N, Aikins ME, Schwendeman A, Moon JJ, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. Front Oncol. 2021 Jun 8;11:631037. doi: 10.3389/fonc.2021.631037. eCollection 2021. Front Oncol. 2021. PMID: 34168976 Free PMC article. Review.
Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice.
Kadiyala P, Carney SV, Gauss JC, Garcia-Fabiani MB, Haase S, Alghamri MS, Núñez FJ, Liu Y, Yu M, Taher A, Nunez FM, Li D, Edwards MB, Kleer CG, Appelman H, Sun Y, Zhao L, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Kadiyala P, et al. Among authors: garcia fabiani mb. J Clin Invest. 2021 Feb 15;131(4):e139542. doi: 10.1172/JCI139542. J Clin Invest. 2021. PMID: 33332283 Free PMC article.
Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development.
Garcia-Fabiani MB, Ventosa M, Comba A, Candolfi M, Nicola Candia AJ, Alghamri MS, Kadiyala P, Carney S, Faisal SM, Schwendeman A, Moon JJ, Scheetz L, Lahann J, Mauser A, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. Expert Opin Investig Drugs. 2020 Jul;29(7):659-684. doi: 10.1080/13543784.2020.1768528. Epub 2020 Jun 4. Expert Opin Investig Drugs. 2020. PMID: 32400216 Review.
RHBDD2 overexpression promotes a chemoresistant and invasive phenotype to rectal cancer tumors via modulating UPR and focal adhesion genes.
Palma S, Raffa CI, Garcia-Fabiani MB, Ferretti VA, Zwenger A, Perez Verdera PV, Llontop A, Rojas Bilbao E, Cuartero V, Abba MC, Lacunza E. Palma S, et al. Among authors: garcia fabiani mb. Biochim Biophys Acta Mol Basis Dis. 2020 Aug 1;1866(8):165810. doi: 10.1016/j.bbadis.2020.165810. Epub 2020 Apr 25. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32339641 Free article.
Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma.
Mendez F, Kadiyala P, Nunez FJ, Carney S, Nunez FM, Gauss JC, Ravindran R, Pawar S, Edwards M, Garcia-Fabiani MB, Haase S, Lowenstein PR, Castro MG. Mendez F, et al. Among authors: garcia fabiani mb. Clin Cancer Res. 2020 Aug 1;26(15):4080-4092. doi: 10.1158/1078-0432.CCR-19-3714. Epub 2020 Apr 24. Clin Cancer Res. 2020. PMID: 32332014 Free PMC article.
20 results