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LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Westendorf K, Žentelis S, Wang L, Foster D, Vaillancourt P, Wiggin M, Lovett E, van der Lee R, Hendle J, Pustilnik A, Sauder JM, Kraft L, Hwang Y, Siegel RW, Chen J, Heinz BA, Higgs RE, Kallewaard NL, Jepson K, Goya R, Smith MA, Collins DW, Pellacani D, Xiang P, de Puyraimond V, Ricicova M, Devorkin L, Pritchard C, O'Neill A, Dalal K, Panwar P, Dhupar H, Garces FA, Cohen CA, Dye JM, Huie KE, Badger CV, Kobasa D, Audet J, Freitas JJ, Hassanali S, Hughes I, Munoz L, Palma HC, Ramamurthy B, Cross RW, Geisbert TW, Menacherry V, Lokugamage K, Borisevich V, Lanz I, Anderson L, Sipahimalani P, Corbett KS, Yang ES, Zhang Y, Shi W, Zhou T, Choe M, Misasi J, Kwong PD, Sullivan NJ, Graham BS, Fernandez TL, Hansen CL, Falconer E, Mascola JR, Jones BE, Barnhart BC. Westendorf K, et al. Among authors: geisbert tw. bioRxiv [Preprint]. 2022 Mar 24:2021.04.30.442182. doi: 10.1101/2021.04.30.442182. bioRxiv. 2022. PMID: 33972947 Free PMC article. Updated. Preprint.
Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection.
To A, Wong TAS, Ball AH, Lieberman MM, Yalley-Ogunro J, Cabus M, Nezami S, Paz F, Elyard HA, Borisevich V, Agans KN, Deer DJ, Woolsey C, Cross RW, Geisbert TW, Donini O, Lehrer AT. To A, et al. Among authors: geisbert tw. Vaccine. 2024 Jan 25;42(3):598-607. doi: 10.1016/j.vaccine.2023.12.053. Epub 2023 Dec 28. Vaccine. 2024. PMID: 38158300
Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.
Zeitlin L, Cross RW, Woolsey C, West BR, Borisevich V, Agans KN, Prasad AN, Deer DJ, Stuart L, McCavitt-Malvido M, Kim DH, Pettitt J, Crowe JE Jr, Whaley KJ, Veesler D, Dimitrov A, Abelson DM, Geisbert TW, Broder CC. Zeitlin L, et al. Among authors: geisbert tw. Sci Transl Med. 2024 Apr 3;16(741):eadl2055. doi: 10.1126/scitranslmed.adl2055. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569014
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus.
Cross RW, Woolsey C, Chu VC, Babusis D, Bannister R, Vermillion MS, Geleziunas R, Barrett KT, Bunyan E, Nguyen AQ, Cihlar T, Porter DP, Prasad AN, Deer DJ, Borisevich V, Agans KN, Martinez J, Harrison MB, Dobias NS, Fenton KA, Bilello JP, Geisbert TW. Cross RW, et al. Among authors: geisbert tw. Science. 2024 Mar 15;383(6688):eadk6176. doi: 10.1126/science.adk6176. Epub 2024 Mar 15. Science. 2024. PMID: 38484056
A Single-shot ChAd3 Vaccine Provides Protection from Intramuscular and Aerosol Sudan Virus Exposure.
Honko AN, Hunegnaw R, Moliva JI, Ploquin A, Dulan CNM, Murray T, Carr D, Foulds KE, Geisbert JB, Geisbert TW, Johnson JC, Wollen-Roberts SE, Trefry JC, Stanley DA, Sullivan NJ. Honko AN, et al. Among authors: geisbert tw. bioRxiv [Preprint]. 2024 Feb 12:2024.02.07.579118. doi: 10.1101/2024.02.07.579118. bioRxiv. 2024. PMID: 38410448 Free PMC article. Preprint.
Monoclonal antibody therapy demonstrates increased virulence of a lineage VII strain of Lassa virus in nonhuman primates.
Woolsey C, Cross RW, Prasad AN, Agans KN, Borisevich V, Deer DJ, Dobias NS, Fears AC, Harrison MB, Heinrich ML, Fenton KA, Garry RF, Branco LM, Geisbert TW. Woolsey C, et al. Among authors: geisbert tw. Emerg Microbes Infect. 2024 Dec;13(1):2301061. doi: 10.1080/22221751.2023.2301061. Epub 2024 Jan 22. Emerg Microbes Infect. 2024. PMID: 38164768 Free PMC article.
The Therapeutic Monoclonal Antibody Bamlanivimab Does Not Enhance SARS-CoV-2 Infection by FcR-Mediated Mechanisms.
Cross RW, Wiethoff CM, Brown-Augsburger P, Berens S, Blackbourne J, Liu L, Wu X, Tetreault J, Dodd C, Sina R, Witcher DR, Newcomb D, Frost D, Wilcox A, Borisevich V, Agans KN, Woolsey C, Prasad AN, Deer DJ, Geisbert JB, Dobias NS, Fenton KA, Strifler B, Ebert P, Higgs R, Beall A, Chanda S, Riva L, Yin X, Geisbert TW. Cross RW, et al. Among authors: geisbert tw. Pathogens. 2023 Nov 30;12(12):1408. doi: 10.3390/pathogens12121408. Pathogens. 2023. PMID: 38133292 Free PMC article.
Animal Models for Henipavirus Research.
Pigeaud DD, Geisbert TW, Woolsey C. Pigeaud DD, et al. Among authors: geisbert tw. Viruses. 2023 Sep 22;15(10):1980. doi: 10.3390/v15101980. Viruses. 2023. PMID: 37896758 Free PMC article. Review.
280 results