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Page 1
Pericyte-expressed Tie2 controls angiogenesis and vessel maturation.
Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, Ruckdeschel T, Hasanov Z, Srivastava K, Hu J, Hertel S, Bartol A, Schlereth K, Augustin HG. Teichert M, et al. Among authors: gengenbacher n. Nat Commun. 2017 Jul 18;8:16106. doi: 10.1038/ncomms16106. Nat Commun. 2017. PMID: 28719590 Free PMC article.
Primary tumor-derived systemic nANGPTL4 inhibits metastasis.
Hübers C, Abdul Pari AA, Grieshober D, Petkov M, Schmidt A, Messmer T, Heyer CM, Schölch S, Kapel SS, Gengenbacher N, Singhal M, Schieb B, Fricke C, Will R, Remans K, Utikal JS, Reissfelder C, Schlesner M, Hodivala-Dilke KM, Kersten S, Goerdt S, Augustin HG, Felcht M. Hübers C, et al. Among authors: gengenbacher n. J Exp Med. 2023 Jan 2;220(1):e20202595. doi: 10.1084/jem.20202595. Epub 2022 Oct 21. J Exp Med. 2023. PMID: 36269299 Free PMC article.
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.
Singhal M, Gengenbacher N, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG. Singhal M, et al. Among authors: gengenbacher n. Sci Transl Med. 2021 Sep;13(609):eabe6805. doi: 10.1126/scitranslmed.abe6805. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516824 Free PMC article.
Tumor Cell-Derived Angiopoietin-2 Promotes Metastasis in Melanoma.
Abdul Pari AA, Singhal M, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke KM, Augustin HG, Felcht M. Abdul Pari AA, et al. Among authors: gengenbacher n. Cancer Res. 2020 Jun 15;80(12):2586-2598. doi: 10.1158/0008-5472.CAN-19-2660. Epub 2020 Apr 17. Cancer Res. 2020. PMID: 32303578 Free PMC article.
Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody.
Singhal M, Gengenbacher N, La Porta S, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG. Singhal M, et al. Among authors: gengenbacher n. EMBO Mol Med. 2020 Jun 8;12(6):e11164. doi: 10.15252/emmm.201911164. Epub 2020 Apr 17. EMBO Mol Med. 2020. PMID: 32302470 Free PMC article.
Endothelial cell fitness dictates the source of regenerating liver vasculature.
Singhal M, Liu X, Inverso D, Jiang K, Dai J, He H, Bartels S, Li W, Abdul Pari AA, Gengenbacher N, Besemfelder E, Hui L, Augustin HG, Hu J. Singhal M, et al. Among authors: gengenbacher n. J Exp Med. 2018 Oct 1;215(10):2497-2508. doi: 10.1084/jem.20180008. Epub 2018 Sep 7. J Exp Med. 2018. PMID: 30194265 Free PMC article.
Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.
Gengenbacher N, Singhal M, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG. Gengenbacher N, et al. Cancer Discov. 2021 Feb;11(2):424-445. doi: 10.1158/2159-8290.CD-20-0122. Epub 2020 Oct 26. Cancer Discov. 2021. PMID: 33106316