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Page 1
Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
Zhang Y, Cedervall J, Hamidi A, Herre M, Viitaniemi K, D'Amico G, Miao Z, Unnithan RVM, Vaccaro A, van Hooren L, Georganaki M, Thulin Å, Qiao Q, Andrae J, Siegbahn A, Heldin CH, Alitalo K, Betsholtz C, Dimberg A, Olsson AK. Zhang Y, et al. Among authors: georganaki m. Cancer Res. 2020 Aug 15;80(16):3345-3358. doi: 10.1158/0008-5472.CAN-19-3533. Epub 2020 Jun 25. Cancer Res. 2020. PMID: 32586981
Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival.
Langenkamp E, Zhang L, Lugano R, Huang H, Elhassan TE, Georganaki M, Bazzar W, Lööf J, Trendelenburg G, Essand M, Pontén F, Smits A, Dimberg A. Langenkamp E, et al. Among authors: georganaki m. Cancer Res. 2015 Nov 1;75(21):4504-16. doi: 10.1158/0008-5472.CAN-14-3636. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363010
Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.
Roodakker KR, Alhuseinalkhudhur A, Al-Jaff M, Georganaki M, Zetterling M, Berntsson SG, Danfors T, Strand R, Edqvist PH, Dimberg A, Larsson EM, Smits A. Roodakker KR, et al. Among authors: georganaki m. Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):569-579. doi: 10.1007/s00259-018-4107-z. Epub 2018 Aug 14. Eur J Nucl Med Mol Imaging. 2019. PMID: 30109401 Free PMC article.
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.
Georganaki M, Ramachandran M, Tuit S, Núñez NG, Karampatzakis A, Fotaki G, van Hooren L, Huang H, Lugano R, Ulas T, Kaunisto A, Holland EC, Ellmark P, Mangsbo SM, Schultze J, Essand M, Tugues S, Dimberg A. Georganaki M, et al. Oncoimmunology. 2020 Mar 9;9(1):1730538. doi: 10.1080/2162402X.2020.1730538. eCollection 2020. Oncoimmunology. 2020. PMID: 32231867 Free PMC article.
Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma.
van Hooren L, Vaccaro A, Ramachandran M, Vazaios K, Libard S, van de Walle T, Georganaki M, Huang H, Pietilä I, Lau J, Ulvmar MH, Karlsson MCI, Zetterling M, Mangsbo SM, Jakola AS, Olsson Bontell T, Smits A, Essand M, Dimberg A. van Hooren L, et al. Among authors: georganaki m. Nat Commun. 2021 Jul 5;12(1):4127. doi: 10.1038/s41467-021-24347-7. Nat Commun. 2021. PMID: 34226552 Free PMC article.
ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
Huang H, Georganaki M, Conze LL, Laviña B, van Hooren L, Vemuri K, van de Walle T, Ramachandran M, Zhang L, Pontén F, Bergqvist M, Smits A, Betsholtz C, Dejana E, Magnusson PU, He L, Lugano R, Dimberg A. Huang H, et al. Among authors: georganaki m. Neuro Oncol. 2022 Mar 12;24(3):398-411. doi: 10.1093/neuonc/noab181. Neuro Oncol. 2022. PMID: 34347079 Free PMC article.
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